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Researchers Eugene Semenov, MD Guihong WAN and colleagues from DermpathMGH investigated an AI approach to identify potential melanoma recurrence, in a npj Journals publication. Read more: massgeneral.org/news/press-rel…

💭 What if we could identify those likely to have early-stage #melanoma recurrence? To this aim, Guihong WAN, @nttn90Very, Eugene Semenov, MD and team used #MachineLearning to analyze clinical and histopathological features. 📕 go.nature.com/3fTPmvJ 📰 bit.ly/3fL6FPK

It was a great talk yesterday with the reporter Sabrina. thecrimson.com/article/2022/1…

I am very happy to share that our paper in Neuroscience has been accepted by the Thirty-Seventh AAAI Conference on Artificial Intelligence (AAAI 2023). Hope the method can be further validated on real patient data.

New research in Nature Medicine from Sasha Gusev, PhD, Toni Choueiri, MD & Matthew Freedman, MD shows for the first time that inherited genetic variations can place patients at higher risk for immunotherapy related toxicities. nature.com/articles/s4159…

1/ Happy to share our latest work looking at the association of germline variants with irAEs in Nature Medicine. An international effort led by🌟@GrohaStefan w/co-seniors #GusevLab Dana-Farber Division of Population Sciences #FreedmanLab & Toni Choueiri, MD Dana-Farber nature.com/articles/s4159… OncoAlert DF/HCC

Excited to share our publication on the prognostic benefits of cutaneous immune-related adverse events, validating our previous population-level findings. Special thanks to Zhang Shijia, Kimberly Tang, Guihong WAN, and the rest of the team. #dermtwitter #MedTwitter

Excited to share our discovery of genetic susceptibility to prurigo nodularis w a measure of polygenic risk! So grateful for the incredible mentorship and collaborative spirit of Dr. Shawn Kwatra Eugene Semenov, MD Sasha Gusev jidonline.org/article/S0022-… Journal of Investigative Dermatology #dermtwitter

Congratulations to Guihong WAN, Mia DeSimone, MD, MPH, and the rest of the team on JAAD Journals study using #ML to predict metastatic recurrence from primary melanoma doi.org/10.1016/j.jaad…

Our paper “The art of centering without centering for robust principal component analysis” has been published in Data Mining and Knowledge Discovery. link.springer.com/article/10.100…

SpatialCells: Automated Profiling of Tumor Microenvironments with Spatially Resolved Multiplexed Single-Cell Data biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

This is my “first” independent work conducted 2+ years ago. The algorithm can be used for some applications, for example, representative selection. link.springer.com/epdf/10.1007/s…

an unexpected Valentines Day gift 😊

Very excited to share our Delphi consensus guidelines to diagnosing dermatologic immunotherapy toxicites. Incredible team effort from more than 30 experts, including Steven Chen 陳持威, MD, MPH, MHPEd Kerry Reynolds, Jarushka Naidoo, and Nicole LeBoeuf.

Extremely proud of the team, especially Guihong WAN, Sara Khattab, MD, and Wenxin Elmon Chen for our The Lancet Oncology study on multi-organ toxicities from checkpoint blockade, providing a roadmap for prognosticating outcomes via the lens of immunotherapy toxicities: tinyurl.com/yc3t7amf

Online First: Multi-organ immune-related adverse events from immune checkpoint inhibitors and their downstream implications: a retrospective multicohort study #immunotherapy #ICIs #irAEs thelancet.com/journals/lanon…

Association of immune-related AEs from ICIs with 6-m survival (landmark analysis) Cf pts w/o irAEs 👉endocrine & cutaneous AEs ass w/⬆️survival 👉respiratory & neurological AEs ass w/⬇️survival 👉No association for other irAE clusters (incl GI, hepatic) #GITwitter #OncTwitter

Our lab University of Maryland School of Medicine is excited to share the discovery of a new skin disease - IL-13+ IL-17+ erythroderma. We also obtained a patent on a diagnostic immunophenotyping platform for the treatment of inflammatory skin diseases #dermtwitter Hannah Cornman nature.com/articles/s4159…

Excited to share our study examining the safety and efficacy of dupilumab for the management of skin #irAEs from #ICIs. Many thanks to Guihong WAN and Sara Khattab, MD who led this study.