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Please RT if you know someone who has students in grades 6-8. With our current online format we are able to accept students from across the country! Kids get to learn about the brain from neuroscientists and perform fun hands-on activities at home!

Another fascinating example of how Class A GPCRs, despite possessing relatively little extracellular real-estate, are critically modulated by their extracellular protein environment! nature.com/articles/s4142…

G protein Go couples to virtually all #GPCRs. It is one of the most abundant proteins in the brain and mutations in it cause #GNAO1 disorder. Here we describe how it regulates neuromodulatory signaling in the striatum. gnao1research cell.com/cell-reports/f…

It’s been incredible watching this develop! Congratulations to all involved, especially Dipak Patil and Kirill Martemyanov Lab!

I've just registered for the GPCR Retreat and I couldn't be more thrilled! I haven't missed one since my first attendance in 2008 and it feels extra personalized this year with my mentors stephen ferguson and Kirill Martemyanov Lab as Keynotes. Looking forward to seeing everyone in person!

A compelling trafficking study demonstrating mGluR7 mobility and subsynaptic localization are predominantly regulated by it’s extracellular domain - suggestive of the integral role of trans-synaptic interactors (like ELFNs) in group III mGluR biology. Glad to see this published!

First day in the lab as a PI @SBRC and Assistant Professor @UManitoba where we’ll study GPCR pharmacology & neuropsychiatric disease! Excited to begin filling this lab with colleagues to share in GPCR enthusiasm - passed down to me from my mentors stephen ferguson and Kirill Martemyanov Lab!

Can’t wait to see this in final form!

Come join our Department! Feel free to reach out to me with any questions!

The recent thread about diplomas in offices got me to thinking about two different offices I’ve visited. One was filled with diplomas and awards—no free space was devoid of an award or diploma. The other was filled with rock music memorabilia…I enjoyed that one immensely.

Very pleased to receive this honour!

Congrats to UM’s Dr. Henry Dunn Henry A. Dunn on being named a Future Leader in Canadian Brain Research. His research explores new treatments for epilepsy, ADHD and autism. Read more about his neurobiology work and the $100k Brain Canada grant: news.umanitoba.ca/um-assistant-p… #UManitoba

An incredible study and resource with many important findings: including reclassification of group I mGluRs and some DREADDs, to name a few! Many congratulations to Kirill, Ikuo, and team.

Very disappointed to be cancelling my trip to the #2023GPCRRetreat tomorrow due to COVID. Was very much looking forward seeing everyone and returning to Montebello - a venue the retreat hadn’t been to in over 10 years and was one of my all time favourites. Enjoy, everyone!

Congratulations to everyone who participated in the University of Manitoba Undergraduate Research Showcase, especially the winners from our department: ✅ 1st Place Poster: Kaden Baskerville (Henry A. Dunn Lab) ✅ 3rd Place Poster: Louis Dela Pena (Joel Pearson Group) news.umanitoba.ca/2023-undergrad…

First day back to work from maternity leave and starting a new job as a Research Associate Pharmacology & Therapeutics University of Manitoba. Lots of feelings but mostly excited to do science again! 🧠🥼🧬🔬#WomenInScience

The 2024 MNN Research Symposium was a resounding success with ~180 Manitoban neuroscientists gathered for the latest in cutting-edge 🧠 research. Special thanks to our amazing sponsors, and Brain Canada Viviane Poupon for joining us to discuss the future of Canadian neuroscience.

Quite the surprise from my lab!

Our latest on GPCR function in the brain. We report that glutamate receptor mGlu4 needs to be properly positioned at synapses of cholinergic interneurons in NAc by cell adhesion molecule ELFN1 to regulate opioid reward. pnas.org/doi/epub/10.10…

We have innovated design of templates for CRISPR/Cas9 editing which allows efficient introduction of epitope tags in vivo. It is a simple hack which we hope to be broadly useful. Work by talented graduate student Chuanping Zhao. nature.com/articles/s4146…