Gene-Wei Li Lab (@geneweililab) 's Twitter Profile
Gene-Wei Li Lab

@geneweililab

Gene-Wei Li's lab @MITBiology, studying the quantitative biology of gene expression. Account run by lab members.

ID: 1494897982130507777

linkhttp://gwli.scripts.mit.edu/group/ calendar_today19-02-2022 04:59:05

41 Tweet

673 Followers

44 Following

Gene-Wei Li Lab (@geneweililab) 's Twitter Profile Photo

We recently found an unexpected deletion in the amyE-back homology arm commonly used for cloning in B. subtilis -- check out the details in our short preprint: biorxiv.org/content/10.110…

Gene-Wei Li Lab (@geneweililab) 's Twitter Profile Photo

Congratulations to Li lab postdoc Andrew Savinov (Andrew Savinov) for receiving an Infinite Expansion Award, recognizing his outstanding service to the MIT community! science.mit.edu/school-of-scie…

Gene-Wei Li Lab (@geneweililab) 's Twitter Profile Photo

Congratulations to Li lab graduate student Manraj Gill on being awarded the William Asbjornsen Albert Memorial Fellowship for his academic accomplishments and his commitment to the MIT community! MIT GradLink MIT Science

Andrew Savinov (@biosavinov) 's Twitter Profile Photo

Was great to have the opportunity to highlight my research program on the power of protein fragments to rewire protein interactions in living cells! MIT Biology

HHMI (@hhminews) 's Twitter Profile Photo

⭐️ Big news! HHMI is investing $300+ million in 26 new #HHMIInvestigators from 19 US institutions. These top scientists will drive groundbreaking research in diverse fields, from neuroscience to immunology to structural biology & beyond. Welcome to HHMI! hhmi.news/4df2eVs

⭐️ Big news! HHMI is investing $300+ million in 26 new #HHMIInvestigators from 19 US institutions. These top scientists will drive groundbreaking research in diverse fields, from neuroscience to immunology to structural biology & beyond. Welcome to HHMI!

hhmi.news/4df2eVs
Andrew Savinov (@biosavinov) 's Twitter Profile Photo

Massive congratulations to my postdoc mentor Gene Wei-Li Gene-Wei Li Lab for being named an HHMI Investigator! Deeply deserved, and I am incredibly excited for the transformative science that lies ahead. Congrats as well to the rest of this amazing cohort. MIT Biology MIT Science

Gene-Wei Li Lab (@geneweililab) 's Twitter Profile Photo

Check out Li lab postdoc Andrew Savinov's (Andrew Savinov) updated manuscript on our computational approach to predict inhibitory protein fragments at scale -- now complemented by extensive new deep mutational scanning experiments. MIT Biology MIT Science HHMI

Gene-Wei Li Lab (@geneweililab) 's Twitter Profile Photo

Thrilled to announce the final version of our paper on computational discovery of protein fragments that can inhibit cellular protein interactions, led by Andrew Savinov (Andrew Savinov), now published in PNASNews. MIT Biology MIT Science HHMI

Andrew Savinov (@biosavinov) 's Twitter Profile Photo

Great to see this piece from MIT Biology highlighting our work on discovering protein fragments to inhibit protein interactions in cells! Thanks Lillian W Eden for the write-up.

MIT Science (@sciencemit) 's Twitter Profile Photo

A new method developed in MIT Biology builds on existing artificial intelligence models to computationally predict protein fragments that can bind to and inhibit full-length proteins in E. coli buff.ly/4k1Ga4N

Andrew Savinov (@biosavinov) 's Twitter Profile Photo

Fantastic to see these physiologically functional protein fragments, congrats all! This aligns with our work demonstrating pervasive functionality of protein fragments in living cells (& ability to predict their binding partners): pnas.org/doi/10.1073/pn… pnas.org/doi/10.1073/pn…

Andrew Savinov (@biosavinov) 's Twitter Profile Photo

Hot on the heels of excellent work from SvenssonLab, more evidence of large-scale generation of functional protein fragments by proteolysis nature.com/articles/s4158… Very exciting to see this convergence with our work showing pervasive function of protein fragments in vivo! (1/2)

Andrew Savinov (@biosavinov) 's Twitter Profile Photo

Agreed, Yunha. Fantastic to discuss the interplay of AI & biology with you, Teja, & great attendees Boston Bacterial Meeting (BBM). Many thanks to David for moderating. Opportunities for new discoveries are vast, esp. if we keep pushing systematic experimental measurements alongside AI models!