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NEW ISSUE ALERT!!! Check out the new Research Papers, Review, Perspective and Outlook Articles online now at Genes & Development. Click on the link for more: ➡️ genesdev.cshlp.org/content/current

1/2: Thrilled to see my lab’s work on #histone chaperones and cellular plasticity featured on the cover of Genes & Development ! The cover was inspired by my love for science and nature. Read our full story in this month’s issue, along with UCR Science News digest! genesdev.cshlp.org/content/39/9-1…

In this Review, Van Alstyne et al. discuss everything Tau, including the pathogenic mechanisms of neurological tauopathies and advances in tau targeted therapies. Learn more here: ➡️ tinyurl.com/gd352551

In this study, Sussman et al. show how epigenetic regulators and histone PTMs function concertedly to control cell fate switching during liver metaplasia and injury response. Learn more here: ➡️ tinyurl.com/gd352420

📽️ G&D Tapes 📽️ G&D author Jonathan Sussman tells us about their new work in #GenesDev showing that epigenetic regulators and histone PTMs work hand in hand to control hepatobiliary plasticity. Learn more here: ➡️ tinyurl.com/gd352420

This Wednesday and Friday, meet the editors of Genome Research. We will be available to discuss your latest research and to answer any questions about the journal. In addition, hear about our upcoming issue on Somatic Mosaicism. #BOG25

Stemming from discussions at a recent Cold Spring Harbor Laboratory Banbury meeting on NF1, this Perspective by Gutmann et al. highlights the current approaches, challenges and future directions to improve patient health and outcomes. #OpenAccess Read the Perspective here: ➡️ tinyurl.com/gd352629

G&D’s Editor-In-Chief, Andy Dillin is attending the AGE Annual Meeting: New Frontiers in Aging Research in Anchorage, Alaska. If you’d like to share your work with us or learn about the journal, feel free to drop by or reach out to [email protected] Genes & Development Dillin Lab

G&D’s Associate Editor, Samantha Cyrill is attending the EMBO Workshop: RNA meets Protein Decay in Vienna, Austria. If you’d like to share your work with us or learn about the journal, feel free to drop by or reach out to [email protected]

In this study, Seppa et al. dissect the mechanisms by which DNA nucleases resect single-strand DNA gaps and regulate repair kinetics, with critical implications for BRCA1-deficiency and PARP inhibitor sensitivity. #OpenAccess Learn more here: ➡️ tinyurl.com/gd352421

In this Outlook, Lee Zou discusses the new work by Seppa et al., comparing single-strand and double-strand DNA repair mechanisms in BRCA mutant cancers. #OpenAccess Lee Zou Read the Outlook here: ➡️ tinyurl.com/gd352827 Read the full story here: ➡️ tinyurl.com/gd352421

In this study, Abaeva et al. describe the role of ribosome-associated quality control factor TCF25 in directing Listerin-mediated ubiquitination for the proteasomal degradation of stalled ribosomes. Learn more here: ➡️ tinyurl.com/gd352389

In this study, Verdu Schlie et al. elucidate the cell cycle kinase, CDK4's key role in mitosis-independent, G1-to-S transition and cell proliferation during development. #OpenAccess Learn more here: ➡️ tinyurl.com/gd352311

In this study, Franklin et al. show that histone chaperones, like the transcription-coupled SPT6 and the replication-coupled CAF-1, control cell differentiation and lineage choice through distinct mechanisms. #OpenAccess Sihem Cheloufi Learn more here: ➡️ tinyurl.com/gd352316

The G&D Editors will be at the Cold Spring Harbor Laboratory Symposium this week, on Senescence and Aging. #cshlsymp25 CSHL Meetings Eric Sawey Samantha Cyrill, PhD Dillin Lab To tell us about your work or learn more about publishing with us, book a 1-on-1 session here: ➡️ doodle.com/meeting/partic…

🎉 Something exciting just landed in the mail! Thrilled to share that one of our illustrations has been featured on the cover of Genes & Development Genes & Development ! Big congratulations to Sihem Cheloufi and her incredible team for their groundbreaking science. It was such a joy

G&D Executive Editor, Dr. Eric Sawey is attending Keystone Symposia #KSNeuroImmune25 in Whistler! If you’re in town, stop by to discuss your work or reach out to Eric Sawey or [email protected] to set up a good time to chat.

In this Review, Solé-Ferran and Losada discuss the mechanisms by which the cohesin complex facilitates chromatin looping and sister chromatid cohesion and their implications for embryonic development and cohesinopathies. #OpenAccess Learn more here: ➡️ tinyurl.com/gd352671