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Please us in beautiful Ventura for the 2025 GRC meeting Mammalian DNA Repair: Fundamental Mechanisms to Human Biology grc.org/mammalian-dna-…. We have a great program, including keynotes from David Pellman and Maria Jasin. Talks and poster slots still available. Apply soon!

Cool role for replication timing and ATR in aging: "IF aging is due to replication stress induced by cryptic DNA damage, it may explain the conundrum why slowly proliferating tissues, eg liver, age faster than highly proliferating tissues eg intestine." cell.com/cell/fulltext/…

In my several decades in science, few moments have been as seismic as when AlphaFold burst onto the scene (seeing the first structure of a K+ ion channel, from Rod MacKinnon, was up there too). We rushed to fold every protein we had been working on, that had no structure, and

Check out our latest pre-print, a follow-up to our 2022 NAR study. Now we have characterized encounters of human DNA polymerase delta holoenzymes with 10 biologically-significant & structurally diverse DNA lesions. Follow 🧵 for key findings & implications biorxiv.org/content/10.110…

I’m thrilled to share this preprint, in which we Baubec Lab engineer DNA damage probes to track DNA damage dynamics by live cell imaging and to probe the DNA damage-associated proteome via proximity ligation: biorxiv.org/cgi/content/sh…

We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home/

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I'm super excited to announce that registrations are now open for the 19th Australian Cell Cycle, DNA Repair and Telomere Workshop. Awesome international speaker line-up, with plenty of locals being invited! Book now to secure your earlybird rate. australiancellcycle.org

🛟Wow cyclic peptides are cool! Excited to share a new publication on "Potent Cyclic Peptide Inhibitors Disrupt the FANCM–RMI Interaction". Work led by @yuhenglau to which we contributed structures and ideas. The top hits mimic native MM2...but in reverse! pubs.acs.org/doi/10.1021/ac…

A transcription balance required for genome stability 🧬⚖️ Our work on RNA Pol II transcription speed control by the DNA helicase RECQL5 and the transcription-coupled DNA repair complex is now on ⁦⁦NatureStructMolBiol⁩ #CryoEM #transcription nature.com/articles/s4159…