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DNA #barcodes are often used for #celltracing but analyses require advanced bioinformatic skills and are time-consuming. This is our solution: upload data, press “Run” and the game is over. Try the #BARseq web-app @ bioinfotiget.it/barseq/ Pietro Genovese Luigi NALDINI COSR Lab

Very interesting technique developed by SR-TIGET for retrieval of viral integrations from liquid biopsies just published Nature Medicine ! Kudos to #Montini's team! #genetherapy #bigdata #lentivirus #viralvectors #invivodelivery #liver #clonaltracking nature.com/articles/s4159…

New post-doctoral position open @ SR-Tiget (Milan, Italy) on #CRISPR #editing of human #hematopoieticstemcells in Dr. Anna Villa’s lab. Great opportunity to contribute to advance this amazing tool toward clinics! linkedin.com/posts/samuele-…

Do you want to describe a particular technique aimed to enhance #CRISPR #editing for #nextgeneration #therapies? JoVE is the leading video journal aimed at increasing the visibility and reproducibility of research. Submit your abstract here! jove.com/methods-collec…

Gene editing of Hematopoietic Stem Cells with Pietro Genovese Dana-Farber/Boston Children’s Cancer and Blood Disorder Center, Boston, USA jobrxiv.org/job/genovese-l… #ScienceJobs #geneediting #genetherapy #immunotherapy

If the food will not go to Italians, Italians will go to the food (and wine). Typical (and nice) Portuguese Dinner with the lab and collegues 🤤 Luigi NALDINI Pietro Genovese @KajasteLab Samuele Ferrari FASEB

Buon viaggio papà.

These are exciting but hard times for #genetherapy . It’s heartbreaking to witness withdrawal of effective gene therapies from the market. They are often the only cure for many rare conditions, saving lives of other human beings. Don’t miss this!

Finally out in Molecular Therapy our new work showing that #mesenchymal stromal cells help "hand-in-hand" #CRISPR/Cas9 edited human #hematopoietic #stem cells to engraft. By Bernardo's lab in coll with Raffaella Di Micco and Luigi NALDINI. bit.ly/3A5LY71. Pic created with DALL·E 2.

Researchers at Ospedale San Raffaele, led by Dr. Maria Ester Bernardo, developed an MSC-based co-culture system to optimize the transplantation outcome of #CRISPR-Cas9 gene-edited human #hematopoietic stem and progenitor cells. 🧬 #OpenAccess | 🔗 bit.ly/3Cjn8mR

"Unless things change dramatically, the millions of people #CRISPR could save will never benefit from it. We must, and we can, build a world with #CRISPR for all." #healthjustice Institute for Geographic Information Science The New York Times nytimes.com/2022/12/09/opi…

eppro02.ativ.me/appinfo.php?pa… ready to share our exciting data tomorrow morning!🩸#ASH22

With #geneediting, researchers restored levels of CTLA-4 in T cells from patients with CTLA-4 insufficiency. In mice, they improved symptoms. ASGCT members involved: @RealDrfox, MbChB, PhD; Claire Booth, MBBS, PhD; Pietro Genovese Pietro Genovese, PhD: ucl.ac.uk/news/2022/oct/….

Gene editing stem cell transplants makes myeloid and T cell therapies safer, according to data at #ASH22 buff.ly/3hCEDqz

Congrats to Zeng Pietro Genovese Daniel Bauer et al. on their paper "Base Editing of Human Hematopoietic Stem Cells." Thanks for using #crispresso2! doi.org/10.1007/978-1-…

Apparently a new investigator 🕵️‍♂️ is on the scenes. Congrats Gabriele for this award there will be many others Pietro Genovese

Excited to share our latest publication about epitope editing in hematopoietic stem cells to enable targeted immunotherapy for acute myeloid leukemia. Congrats to Gabriele Casirati and all collaborators for this amazing work. nature.com/articles/s4158…

Very proud of your achievements Samuele Ferrari !! It has been a privilege contributing in mentoring such amazing young scientist!

My postdoc work in the Daniel Bauer lab is out Nature Biotechnology! We found that the limited nucleotide pool in hematopoietic stem and progenitor cells (HSPCs) constrains reverse transcription and thus prime editing (PE). nature.com/articles/s4158…

Thrilled to see the great work from Daniel Bauer lab featured in Nature Biotechnology! The discovery that a limited nucleotide pool in HSPCs constrains prime editing is a leap forward in gene editing technology. A huge shoutout to Sébastien Levesque and the entire team!