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i am so excited about our open source inexpensive, sub-cellular capture, do-it-yourself Open-ST that transforms tissues into virtual tissue blocks in 3D - IDing pathways & gene programs driving phenotypes. a huge congratz to the team! cell.com/cell/abstract/…

The mirrored room in the palace of Würzburg, Germany

Ha! AI models require data on genuine human interactions , or they collapse! disq.us/t/4pugllq

Human organoids with an autologous tissue-resident immune compartment | Nature nature.com/articles/s4158…

We congratulate Dr Jakob Zimmermann on the #ERCStartingGrant! He is investigating the interaction between intestinal flora and the immune system @wue_si. Jakob Zimmermann European Research Council (ERC) uni-wuerzburg.de/en/news-and-ev…

Welcome Jakob, really great to have you joining the team WüSI - Systems Immunology Würzburg and @CRC_DECIDE

Not the first and likely not the last review on tuft cells. But for sure the most recent one, published in Nature Reviews Gastroenterology & Hepatology: Kalle and Xiaogang Feng(冯小刚) did a great job summarizing recent findings related to tuft cells nature.com/articles/s4157… full-text access: rdcu.be/dVaOi

GPR34 is a metabolic immune checkpoint that can be targeted to enhance ILC1-based immunotherapies Nature Immunology nature.com/articles/s4159…

In Journal of Experimental Medicine, Colin Sparano, Darío Solís-Sayago et al. TuguesLab University of Zurich reveal that tissue-resident NK cells produce their own TGF-β1 to sustain residency in glandular tissues, providing local antiviral protection. hubs.la/Q0303z7B0 #inflammation #LymphocyteBiology

Tissue-resident NKs in glands depend on their own TGFb! Congrats Colin and Sonia TuguesLab - great work! and stimulating discussions - thanks a lot!

Zelensky has thanked Trump, Congress, and the American people many times. But let's be clear: when Trump and Vance said that THEY are trying to help Ukraine right now, and need to be thanked for the work personally, there are reasons to wonder. 1/ THREAD

Differentiation of tissue-resident NK cells: Why origin and context matter cell.com/immunity/fullt… Free access: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

Differentiation of tissue-resident NK cells: Why origin and context matter dlvr.it/TJYYzW

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals Science Magazine Kastenmüller Lab Georg Gasteiger science.org/doi/epdf/10.11…

A second priming phase promotes high-affinity CD8 T cells by coordinating CD4 help and the relay of IL-2 in subfollicular LN niches. Congrats to WüSI - Systems Immunology Würzburg’s Kasia, Deeksha, Kastenmüller Lab Georg Gasteiger . science.org/doi/10.1126/sc…

#Immunology out now Science Magazine After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/lCPsea3 By Jobinet al.

Imaging the Immune System! Amazing line-up at the 6th Edition of this International Meeting. Join us June 11-13 for Wine and Science at the historic Julisuspital in Würzburg, Germany imaging-immune-system.wuesi.com

Seeing is believing! Few spots left for Imaging the Immune System—the 6th edition of this world-class meeting. Don’t miss the amazing speakers, wine, and science 🍷🧬 📅 June 11–13 📍 Historic Juliuspital Winery, Würzburg, Germany 👉 imaging-immune-system.wuesi.com

Kudos Matteo and team Iannacone Lab, really intriguing work!

Check this out and join a very collaborative and enthusiastic crowd WüSI - Systems Immunology Würzburg