In our revision, we used plexDIA to analyze >150 single cells on two instruments: timsTOF SCP and first generation Q Exactive with 15 and 30 minute active gradients. We demonstrated... (🧵)

To accomodate more attendees, the 5th Single-Cell Proteomics conference will add a real-time YouTube broadcast. The YouTube broadcast will be available to colleagues who exceed the on-line limits. Attending SCP2022 is free but requires registration single-cell.net/proteomics/scp…

Excited to share that our story about human SLFN11 is out in Nature Communications Awesome team effort with Felix Metzner, Michael Kugler and Katja Lammens at the hopfnerlab, Gene Center Munich

Our new preprint with #Bruker introduces synchro-PASEF, a highly efficient DIA scan mode that follows the ion cloud naturally. Fragments are directly linked to precursors via precursor slicing, generating pure, DDA-like ms/ms spectra. doi.org/10.1101/2022.1…

Synchro-PASEF out now in MCP: a very fast & sensitive new scan mode for #timsTOF Bruker. It links fragments to precursors enabling the deconvolution of DIA space to DDA-like ‘pure fragmentation spectra’ by slicing precursors in ion mobility dimension. doi.org/10.1016/j.mcpr…

Fresh on bioRxiv: @sophiaMaedler and I developed ✨SPARCS✨, a technology for microscopy-based genome-wide genetic screens in human cells🔬🧬 biorxiv.org/content/10.110… This work was enabled by the amazing collaborative environment created by HornungLab and Matthias Mann Lab. 🧵👇

We've got something exciting to share before #ASMS2024! But first, how confident do you feel about your DIA search? #TeamMassSpec

AlphaDIA enables End-to-End Transfer Learning for Feature-Free Proteomics biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

A novel hybrid high speed mass spectrometer allows rapid translation from biomarker candidates to targeted clinical tests using 15N ... biorxiv.org/cgi/content/sh… #biorxiv_biochem

1/7 Matthias Mann Lab and Georg Wallmann Georg Wallmann are proud to announce alphaDIA, our open source, next generation DIA search engine. Check out the preprint bioRxiv biorxiv.org/content/10.110…

Cellular states prior to stimulation will be predictively associated to outcomes. By linking variable proteomes to responses, we may identify regulators. biorxiv.org/content/10.110… Here, we use single-nucleus proteomics to identify regulators of LPS-induced protein transport🧵

We just release alphaDIA 1.8.2 including some new step-by-step guides for #Proteomics. Learn how to: • Run DIA searches from the GUI • Create custom PTM models with DIA transfer learning • Evaluate model performance with detailed metrics alphadia.readthedocs.io/en/latest/guid… #TeamMasSpec

Please RT! Help LogMeIn understand the impact of allowing scammers to easily use their product: troyhunt.com/2012/06/how-lo…

Pasteception pastebin.com/YNAAb0NG

Did Microsoft really need to ship a whole new Windows just to fix shellshock? See, this is what I've been saying Linux patching is superior.

I am not a parody account. How many stupid jokes about writing songs about ex-boyfriends do you see? I'm Taylor Swift. InfoSec Professional.

Proposed Applications for New AR Goggles #chartgeist instagram.com/p/1gswvpFWqY

Nächste Woche Verfahrenseinstellung, Range fliegt, Markus Beckedahl 50.000€ reicher, SPD -5%, CDU +5% und so haben alle was davon. #Landesverrat

Satire darf bei rot über Ampel fahren. #satiredarfalles

Neben der türkischen Botschaft in Berlin gesehen. genial #freeboehmi #Satiredarfalles #Humorlosekackbratze