🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

ACT NOW! Tomorrow, Congress will vote on a CR that will result in a 57% cut to CDMRP budget and will impact the Research Programs that support urologic topics such as prostate cancer, kidney cancer, bladder cancer, kidney health, and more. CDMRP provides funding that accelerates

Please protect funding for the CDMRP, including the Prostate Cancer Research Program! Cutting it would slow life-saving research and impact patients who need better treatment options. Please ensure that CDMRP is fully funded. Thanks! Kweisi Mfume John James Rep. Andy Harris, MD

Angiocrine signaling is rocking - pericrine signaling is the new kid on the block: Hepatic stellate cells control liver function (‘HSCs make the liver great again’) – now published nature (nature.com/articles/s4158…). Fantastic collaboration with the Robert Schwabe lab Columbia Univ.

We’re hiring a chief development officer to lead fundraising efforts to support NBCC’s operations, and a corporate and foundation relations manager to cultivate, solicit, and steward corporate and foundation relationships and cause-marketing partnerships. nbcc.info/jobs

Why do circulating ovarian cancer clusters hve #ECM? How do clusters survive confining anatomies? Do clusters show heterogeneity in mechanics? Team led by Tavishi Dutt & Jimpi Langthasa frm IISc Bangalore answer in bit.ly/41OWZsb Ack: IFCPAR/CEFIPRA Ministry of Electronics & IT DBT/WT India Alliance

Ever wondered what the lonely histone H3C110 does? We found that it’s lost in many fungi. Adding it back boosts histone H3 copper reductase activity, rescues iron defects and modulates lifespan, suggesting an evolutionary tradeoff between these effects. science.org/doi/10.1126/sc…

Modulating AP-1 enables CAR-T cells to establish an intratumoral PD-1+ Tcf1+ stem-like reservoir and overcomes resistance to PD-1 axis blockade biorxiv.org/content/10.110… Shivani Srivastava

Powerful new story from the Srivastava Lab Shivani Srivastava

Gratifying to now see our pericrine liver work in the print version of nature (nature.com/articles/s4158…). Massive piece of work with 651 display items (174 main, 477 supplement). Feels like we are publishing books and not papers. Thanks to Robert Schwabe for great collaboration!

Interested in the mysteries surrounding metastasis evolution? This perspective in Nature Reviews Cancer is my best attempt at proposing a framework that could help advance our thinking about the topic. Well. At least it helped advance my own thinking. 😅 nature.com/articles/s4156…

1/ Excited to share CellFlow, a new approach for complex perturbation modeling in single-cell genomics based on flow matching. From cytokine screens to cell fate and organoid engineering, we show CellFlow’s broad power across many diverse tasks. 👉 Paper: biorxiv.org/content/10.110…

What factors enable CAR-Ts to respond to checkpoint blockade, and can they be engineered to be more sensitive to enhancement? We explore this question in our lab’s first pre-print, led by MSTP student AJ Snyder with great collaborations with Evan Newell and Scott Furlan. 1/

#AACR25 come check out SY20 Wednesday at 10:15am to discuss Lymph Nodes and Lymphoid Structures in Cancer with me, Tullia Bruno, PhD and Ziv Shulman Lab !!

My favorite Berkeley Alum Dan the MF Man Rubinoff discussing one of his more amazing discoveries:

Such an honor to present Senator Senator Patty Murray with an award on behalf of National Breast Cancer Coalition for her unwavering support of NBCC’s legislative priorities, especially the DoD Breast Cancer Research Program. We’re very lucky to call her our Senator.

Beautiful and compelling new work from the Perera Lab:

Between alarms and sheltering, I learned last night that my postdoc mentor, Professor Atul Butte Atul Butte, has passed away, and he is only 55 years old. This is devastating news 💔. Atul was a giant in so many ways. He was a visionary leader in translational bioinformatics

Patrick Paddison and friends lighting it up!

New paper out! We show amino acid restriction triggers genome-wide H4K20me1 loss and MYC activation—priming cells for rapid protein synthesis upon refeeding. A chromatin-based strategy for surviving nutrient stress with implications for MYC-driven cancers. cancerandmetabolism.biomedcentral.com/articles/10.11…

Excited to share our new study on how resistance to AKT inhibition is linked to lineage differences within breast cancer 👇🏽biorxiv.org/content/10.110… and also surprisingly/worryingly good AI generated podcast 🎧notebooklm.google.com/notebook/28ebc…