Our paper is online!! #SignalingProfiler is a novel method that allowed us to discover the key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients nature.com/articles/s4137…

Thanks to the great effort of Giorgia Massacci and @vero_venafra, our lab, collaborators, Natalie Krahmer , Martin Boettcher , and Livia Perfetto!

Our lab website!!! francescasaccolab.org

Very proud to share this work of my group where we integrate #phosphoproteomics and our #signalingProfiler pipeline to unveil chemoresistance in #AML in collaboration with Livia Perfetto , Martin Boettcher and the haematological group @madgeburg!nature.com/articles/s4137…

Here we are!

So grateful to have been at the Max Planck Institute of Biochemistry in the Mann's lab! A great and very inspiring visiting period to learn the most recent and advanced MS-based workflows!!

Happy to be at the "Proteomics in cell biology and disease mechanisms" conference at EMBL and share my work with such amazing people! #EWCSProteomics EMBL Events

Interested in CDK1 substrates and regulators? Read our review! nature.com/articles/s4141… With Giorgia Massacci and Livia Perfetto

Check out our latest review! We meticulously curated information from a wide array of peer-reviewed articles and databases to provide a global overview of the role of CDK1 kinase beyond the cell cycle regulation. nature.com/articles/s4141…

Sabato 11 novembre avrò il piacere di essere al fianco di Fondazione AIRC per la ricerca sul cancro per i #giornidellaricerca. Vi aspetto a Roma in Piazza Bologna, dove potrete acquistare i #cioccolatinidellaricerca e contribuire in modo concreto alla ricerca sui tumori.

Happy to share our work in collaboration with Tommaso Schirinzi, Maria Wahle and Maxi Zwiebel from Matthias Mann Lab, Livia Perfetto and @vero_venafra. Here, we show that blood cells, from Parkinson disease patients, display a stage-dependent remodelling of their phosphoproteome.

Huge congratulations to Giorgia Massacci!!! sciencedirect.com/science/articl…

Excited to share our new work "Stage-dependent phosphoproteome remodeling of Parkinson's disease blood cells". Thanks to our collaborators Tommaso Schirinzi Tommaso Schirinzi, Maria Wahle Livia Perfetto, Maximilian Zwiebel!! sciencedirect.com/science/articl…