🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Our review on apoptosis-induced ERK waves is out in Seminars in Cell & Developmental Biology! Thanks to PertzLab, Maciej Dobrzynski & all colleagues studying ERK dynamics! sciencedirect.com/science/articl…

Honored to celebrate Dr. Rakesh Jain’s inspiring AACR 2025 Lifetime Achievement Award! 🏅 His keynote on “Normalizing the Tumor Microenvironment” was a masterclass in translational science. A proud moment for Edwin L. Steele Laboratories and Mass General Cancer Center! AACR #AACR25 Ludwig Cancer

⏱️ Clock is ticking! Final call for abstract submissions for #EANO2025 in #Prague. Don't miss this chance to share your work contribute to the advancement of #NeuroOncology. Submit now via our official event website: eano.eu/eano2025/ until May 6, 2025, 23.59 CEST!

TIGIT expression dictates the immunosuppressive reprogramming of myeloid cells in glioblastoma biorxiv.org/content/10.110…

Popular methods like UMAP & t-SNE are stochastic and distort data structure. Bonsai - a novel method - builds trees to relate high-dimensional objects, accounting for measurement noise. biorxiv.org/content/10.110…

Online Now: Regulating the fate of tumor-associated macrophages dlvr.it/TKg0yq

Thanks Paolo G. Decuzzi for the kind invitation of yesterday!! It was a wonderful day, full of very interesting meetings! IIT is really a great institute with top level scientists!!

Online Now: Brain metastasis: From etiology to ecotypes dlvr.it/TKjkbd

Excited to share our review: "Cell-type deconvolution methods for spatial transcriptomics" in Nature Reviews Genetics nature.com/articles/s4157… (read free rdcu.be/el0Ka) Congratulations Lucie Gaspard-Boulinc and Luca Gortana for this awesome work ! Institut Curie Inserm

p16-expressing microglia and endothelial cells promote tauopathy and neurovascular abnormalities in PS19 mice: Neuron cell.com/neuron/fulltex…

Dr. Rakesh Jain @SteeleLabsMGH shared insights from his decades-long work on vascular normalization—from concept to clinic. His lecture emphasized strategies to improve tumor vessel function and how these principles are transforming cancer therapy at #AACR25 Harvard Medical School

💡Recently published in Neuro-Oncology: Charting the Single-Cell and Spatial Landscape of IDH-Wildtype Glioblastoma with GBmap. Read full article 👉 doi.org/10.1093/neuonc… #EANOessentials #Neuro-Oncology #glioma #Glioblastoma

📢 Preprint alert! (3rd TIME Lab ms in 2 weeks!) In collaboration with Christopher Patzke, grads Maksym Zarodniuk (Maksym Zarodniuk) and Anna Wenninger demonstrate cellular & molecular mechanisms by which mechanical compression (e.g., from tumors, TBI) damages neurons.biorxiv.org/content/10.110…

It is so exciting to see this multidisciplinary #mechanoneuroscience study in human neurons, building on our original paper where we first showed the mechanical impact of tumors on neurological performance, led by Giorgio Seano, Hadi T. Nia, and Kyrre Emblem nature.com/articles/s4155…

"The Microbiome for Clinicians" a new, open-access review of progress, limitations, and next steps Cell cell.com/cell/fulltext/…

The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:

Online Now: The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets dlvr.it/TL3d9s

How exercise protects the brain through neurovascular-associated astrocytes and neuroplasticity: Results of elegant single cell/nuceli studies in the experimental Alzheimer's model Nature Neuroscience nature.com/articles/s4159…

🚀 Xaira Therapeutics has just dropped a game-changer for AI-driven biology. Today, we unveiled X-Atlas/Orion, the largest publicly available genome-wide Perturb-seq dataset to date—spanning 8.4 million single cells with perturbations across all ~20,000 human protein-coding

CellMarker 2.0 An updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data http://117.50.127.228/CellMarker/index.html A nice resource for cell type markers for supervised clustering😁 Nucleic Acids Res 2023 academic.oup.com/nar/article/51…