Endogenous DNA breaks at neuronal enhancers: novel links to neurodegeneration? Great fun writing this preLight with Sree Rama Chaitanya. prelights.biologists.com/highlights/neu…

Online now! A #natural single-guide #RNA that directs Cas9 to #transcriptionally repress its own #promoter bit.ly/2JXD71l

Don't forget to check out preLights - the preprint highlights service supported by our publisher The Company of Biologists. Our community of scientists select, highlight and comment on preprints they feel are of particular interest to the biological community: ow.ly/EVGi50D8qUZ

FUSzy ways of DNA damage response. prelights.biologists.com/highlights/fus… By preLighters Sree Rama Chaitanya and Giuseppina D'Alessandro on preprint from Brunno Rocha Levone et al. with author's response

Exciting opportunity to join a fast growing biotech with a focus on developing new DDR inhibitors fro cancer therapy! #biotech #drugdiscovery #research #DDR artiospharma.com/career/scienti…

The RING sparkle enlightens a new route for BRCA1 recruitment to DNA lesions. PreLight by Giuseppina D'Alessandro on a new preprint from @durocher1 prelights.biologists.com/highlights/two…

Our latest Review on CRISPR-Cas9 screen contributions in the #DNADamageResponse field is now available at Nature Reviews Molecular Cell Biology ! Co-Written with Steve Jackson Lab, Samah W. Awwad, John Thomas and Vipul Gupta :)

Celebrating with our Aldo Bader on his Wellcome Early-Career Award, to continue his exciting research into defining the mutagenic impacts of #DNA resection during double-strand break repair. Congratulations 🥳

And if you want to join the team, check out cruk.cam.ac.uk/job/research-a…

Happy to share our work showing that RAD54L2 promotes genome stability by countering the formation of toxic TOP2 cleavage complexes. Great teamwork with Steve Jackson Lab @guidozagnoli Almudena Serrano-Benítez Sean Richards D. Morales and with P. Beli and J. Nitiss groups science.org/doi/10.1126/sc…

Latest paper from Artios, describing our suite of DSBR reporter assays! academic.oup.com/nar/advance-ar…

We made it! Our latest manuscript is now live in Nature Communications, give it a read! nature.com/articles/s4146…

New DPC goodies for your Christmas stockings ! 🎄 🔔 Congrats @cjcarnie and co.! We love TOPORS biorxiv.org/content/10.110…

We are excited to share our new study in Nature Cell Biology revealing that Cockayne Syndrome proteins CSA and CSB are required for the repair of toxic DNA-protein crosslinks (DPC) and we describe a novel transcription-coupled DPC repair pathway, nature.com/articles/s4155…

Check out this great work from my amazing colleagues @cjcarnie, Chloe Palma-Chaundler and Max Gotz in another fruitful collaboration between Steve Jackson Lab and @stingele_lab!

Thrilled to see our work on murine oesophageal #Epithelioids published in Nature Genetics, after many years of hard work alongside Albert_Herms during our postdoc at Phil Jones' lab @Sangerinstitute and built on the foundational work by Maria Alcolea nature.com/articles/s4158…

Happy to share that our recent work on the role of USP37 in counteracting the ubiquitylation and premature disassembly of stressed replisomes by TRAIP is now out. A fantastic collaboration with Olga Kochenova in Johannes Walter,Grant Stewart,Steve Jackson Lab nature.com/articles/s4146…