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🚨Can exercise reduce fatigue in people living with kidney disease? Thanks to Jamie Hugo Macdonald and Lisa ANCLIFFE for help putting this together 🔗journals.lww.com/co-clinicalnut… ...or DM me

Think of LDL like ‘pack-years’ in smoking 👉🏼 Total exposure over time matters! ⏳ Lowering LDL earlier reduces plaque burden & CV events 📉 ⏰ Prevention starts now! 🫀🔥 🔗 nature.com/articles/s4156… #Lipidology #Atherosclerosis American College of Cardiology European Society of Cardiology Journals European Atherosclerosis Society #MedEd

Striving for early effective glycaemic and weight management in type 2 diabetes Excellent review by Dr. Alice Cheng & Stefano Del Prato et al dom-pubs.onlinelibrary.wiley.com/doi/full/10.11…

Front-loading calories may be the key to better weight loss. In this study, eating most calories at breakfast led to: 📉 2.5x greater weight loss (8.7 vs. 3.6 kg) 💪 Better insulin sensitivity (-57 vs. -33%) 🩸 Lower triglycerides (⬇️ 34%) 🍽 Less hunger, more satiety 1/13 🧵

Dr Dr Hannah Young shares her advice for women considering a #career in #science for #IDWGS: “Do your homework, can you see female leaders? What's the culture like? I’m very lucky to work at LDC with many fantastic women to draw inspiration & support from, & investment in staff.”

Lifestyle Intervention Effects on Blood Pressure 1️⃣ Regular exercise: 4/8mmHg 2️⃣ Reduced alcohol intake: 4mmHg 3️⃣ Weight loss: 5mmHg 4️⃣ Reduced sodium intake: 5/6mmHg 5️⃣ Increased potassium intake: 3/4mmHg These lifestyle changes led to: 1) 15% reduction in all-cause mortality

In Young Adults, Type 2 Diabetes Opens Doors to Other Diseases, Sooner medpagetoday.com/resource-cente… Great work Jono Goldney 👏

Today March 4, is World Obesity world obesity day. People with obesity are not bad, they’re not morally bereft, they are fighting biology #obesityisnotachoice

If you wanted to know more about #LanguageMatters in #Diabetes? The website below has all the info you need (H/T Jazz Sethi for the amazing work!) And beyond 🇬🇧? Versions of it from the following: 🇬🇷🇮🇹🇩🇪🇹🇷🇵🇹🇸🇪🇦🇺🇨🇦🇫🇷🇿🇦🇳🇱🇵🇰🇮🇪 And of course 🇮🇳 Plus one exclusively on

Fantastic to work with so many inspirational women in @ldc

🏆We're proud to announce LDC Co-Director, Melanie has been chosen to receive the 2025 Outstanding Achievement in Clinical Diabetes Research Award from American Diabetes Association. Melanie is only the second woman to receive this prestigious award! Read more: leicesterdiabetescentre.org.uk/news-blog/2025…

What is the impact of switching from annual to biennial diabetic eye #screening for those at low risk of #DiabeticRetinopathy? Researchers Population Health Research suggest a simple point-based score to identify how often people at low risk should be screened link.springer.com/article/10.100… 🔓

Network meta-analysis SGLT2 inhibitors seem more cardioprotective in older than in younger people despite smaller reductions in HbA1c GLP-1 receptor agonists seem more cardioprotective in younger people. jamanetwork.com/journals/jama/…

I often get asked about UTIs with SGLT2i which were not observed in the trials. Great to see this study showing that in routine clinical care, SGLT2i initiation is not associated with ⬆️ risk of UTI compared with GLP-1RA initiation. diabetesjournals.org/care/article-a…

Phase 3 trial of oral #Orforglipron ; lowering A1C by an average of 1.3% to 1.6% across doses Once-daily oral pill reduced weight by an average 16.0 lbs (7.9%) at the highest dose in a key S’ endpoint tctmd.com/news/oral-glp-… TCTMD Mamas A. Mamas Caitlin E. Cox Shelley Zieroth

In 1780, Paul Cuffee, his brother & 5 other Black men petitioned the Massachusetts legislature demanding the right to vote. He won free black men the right to vote in Massachusetts on the basis of "No Taxation Without Representation." THREAD

Pleased to present our work from 🌱Leicester Diabetes Leicester Real World Evidence (LRWE) Research at Leicester's Hospitals on weight loss interventions in CKD....most of the work really done by Jono Goldney !

Vitamin D supplementation may reduce respiratory infections in children, mortality in older adults, and diabetes progression in prediabetics, with inconclusive evidence for other benefits. ja.ma/4n0yEZh

Significantly higher associated cardiovascular risk in people with diabetes who delay statin therapy ahajournals.org/doi/10.1161/JA… Mamas A. Mamas

🚌 No GLP‑1 muscle protectors for ages… …then 3 come at once. 💥 EMBRAZE adds to BELIEVE & COURAGE — all hitting #ADA2025 💪 Apitegromab + tirzepatide (Phase 2) 🧍 Lean mass preserved: • +4.2 kg vs tirzepatide alone • ~55% preserved vs ~30% typical • 85% of weight loss