Happy to share with you, our piece on how the molecular membrane fission machine - dynamin is regulated by 'gears' in its membrane binding PH-domain. Thomas Pucadyil and I curated this brief review for Current Opinion in Cell Biology. Now online: authors.elsevier.com/c/1hPJK3PA3sV0…

sciencedirect.com/science/articl… New review from the lab. I propose that the roles of different lipid structures, besides affecting membranes and associated proteins, have important roles in dictating lipid metabolic fates and deciding which additional structural features will be added.

One hundred years ago, the French pharmacologist Gabriel Bertrand united all the biological molecules that we now understand as structurally and/or functionally related to fats, such as #cholesterol, waxes and #phospholipids, under a common name, lipides. asbmb.org/asbmb-today/sc…

My lab is looking for a research technician and postdocs. theaugustinelab.org/positions Application link: employment.ucsd.edu/lab-assistant-…. Please help spread the word.

Thrilled to share our work on how type V-K CRISPR-associated transposases (CASTs) select their target sites, now published in Science Magazine! science.org/doi/full/10.11… In this study, we've enhanced the accuracy of type V-K CASTs up to 99%.🧵 on the bioRxiv version below:

We’re happy to share the new preprint from the lab. Great job done by Sarah (Sarah Salame), Hasna, and Gregor (Gregor Jose) from the lab, together with Lucile and Delphine from the biomolecule analysis platform of the institute (IPMC). doi.org/10.1101/2024.0…

Incredibly honored to named a #SloanFellow. Thank you to the Sloan Foundation! We are looking for postdocs. Please help to spread the word.

“Thrilled to share the big news: This Fall, Prajakatta Mulay & I are joining FLORIDA🐊as Assistant Professors!” I will lead the Narayananlab.com as Ten. Track Assistant Professor UF Chemistry and Prajakatta will start as an Instructional Assistant Professor UF Materials Science | Nuclear Engineering Program #NewPI

This microscope can simultaneously sequence an individual cell’s DNA and pinpoint the location of its proteins with high resolution — all without having to crack the cell open and extract its contents go.nature.com/3Y5jqGG

Scientists have designed a new form of insulin that can automatically switch itself on and off depending on glucose levels in the blood go.nature.com/3A14Yrk

Now published, SHUBHAM SINGH identifies PLD3/4 as synthesizing BMP, a lipid crucial for #lysosome #lipid #metabolism and #brain health sciencedirect.com/science/articl…

📢 Open PhD position as part of #MSCA network of 17 students ComeInCell Interested in exploring membrane stability/repair & #condensates ? Check out & apply: 👉bit.ly/4fd8HRU The project will include secondments at Andela Saric, Carlos Marques & Nature Communications

I am thrilled that our work on MemGraft probes for “permanent” fluorescent labelling of plasma membranes is out in JACS Au! We established a concept of lipid-directed covalent labeling of plasma membranes. Open access: pubs.acs.org/doi/10.1021/ja… MemGraft probes allow cell fixation,

🔥🔬"Measuring plasma membrane fluidity using confocal microscopy" in Nature Protocols🔬🔥 doi.org/10.1038/s41596… Thanks to the authors for the detailed protocol! Pablo Carravilla Jan Schlegel Ellen Sjule Franziska Ragaller Florian Weber Cenk Gurdap Taras Sych Erdinc Sezgin

Excited to share our new study Cell Reports identifying the role of atherogenic 7-ketocholesterol in Piezo1 modulation. IPMC CNRS 🌍 cell.com/cell-reports/f…

Big congrats to Raphaël Rodriguez, his lab, and the whole team of collaborators on a fantastic paper on mobilizing lysosomal iron to drive ferroptosis: nature.com/articles/s4158…

”I love failure.” Medicine laureate Richard Roberts shares some of his best advice to young students and how to stay creative. Robert participated at our recent Nobel Prize Dialogue in Tokyo, watch the full event here: bit.ly/4izEe1q

Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism" —the 1st human to undergo custom genome editing —outgrowth of decades of NIH funded research nejm.org/doi/full/10.10… nejm.org/doi/full/10.10… NEJM

hanging out with strangers in a campus pub should be considered part of the serious process of thinking

Membrane Biology: Nothing can replace polyunsaturated lipids Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane. elifesciences.org/articles/10824…