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Congrats to the latest The Guilak Lab PhDs, Alireza Savadipour, Neda Rashidi, and Zainab Harissa!

Check out our latest study on the #mechanobiology of chondrocytes - mapping out the mechanome in response to activation of TRPV4 or Piezo1, in contrast to IL-1. Great work by MaybeItsBob, Daniel Palmer, & Jordan Kassab in collaboration with Bo.博 of WashU Center of Reg Med!

Congrats Lauryn Braxton on an amazing and successful thesis proposal!

New The Guilak Lab group photo!

Check out the latest from The Guilak Lab on maternal health and reproduction in the MSK system - Exciting new findings on the effects of maternal and grandparent diet on skeletal health!

Did you know that obesity causes cellular senescence in the joints? Check out our latest gene therapy - an enzyme called fat-1 that converts inflammatory fatty acids into anti-inflammatory ones - and reduces osteoarthritis and senescence! pnas.org/doi/10.1073/pn…

👏🏻👏🏻👏🏻 Farshid Guilak The Guilak Lab

Yes, it's the time of year for Farshoween...

Shameless plug: If you haven't tried it, I highly recommend this new party/meeting planning app, Partiful. It's the app of the day on the App Store - download for free! apps.apple.com/us/story/id177…

🎉New publication🎉 Ever wondered how cells transduce mechanical signals to the nucleus? Check out our latest publication from the The Guilak Lab in collaboration with Dr. Marina Danalache lab: doi.org/10.1016/j.bbrc…

I've been many things, but this is a first... 🥸

Ph-done! Congrats Dr Daniel Palmer on an amazing PhD and defense!

Members of the Guilak Lab have been hard at work this holiday season! 🎄 The team decorated gingerbread houses with their special signature - a mustache, in honor of their leader, Farshid Guilak, Ph.D. #ThankYouDonors #ShrinersChildrens Shriners Children's The Guilak Lab Farshid Guilak

Proud and excited to be part of Shriners Children's Shriners Children’s St. Louis!

Huge congrats on an amazing dissertation and defense, Dr. Erica Ely Erica Ely! It's #Piezo month at The Guilak Lab!

Congrats to Gabi Marushack and Alireza Savadipour & team for our latest The Guilak Lab paper showing that polyunsaturated fatty acids alter cell membrane properties & inhibit chondrocyte #mechanotransduction by #Piezo1 and #TRPV4. faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

A tip of the fez to the Edgar County Shrine Club for their incredible donation to the research department at Shriners Children’s St. Louis. #Shriners #donation

Obesity has a distinct impact on the progression of OA. We showed significant loss of protective synovial lining macrophages in the synovium 3 days after joint injury, with a significant restoration in normal-weight but not in obese mice ard.eular.org/article/S0003-… Farshid Guilak

Join us today for our AOC Thought Leaders Webinar: Managing the Research Enterprise — for anyone navigating the evolving landscape of academic orthopaedics. April 24 | 4:00 PM ET Register Here: lnkd.in/eTrzEem6 Joint the AOC at myaocconnect.com!

Congrats to Amanda Cimino for her latest paper creating a chronogenetic gene circuit that automatically delivers anti-inflammatory biologic drugs in response to inflammation or circadian signal! jbioleng.biomedcentral.com/articles/10.11…