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Please check our new paper-Skeletal muscle antagonizes antiviral CD8 T cell exhaustion advances.sciencemag.org/content/6/24/e…

Have a look at our paper: T Cell Factor 1 Suppresses CD103 Lung Tissue-Resident Memory T Cell D... sciencedirect.com/science/articl…

We are hiring postdoctoral fellows at the German Cancer Research Center (Mainz campus). jobs.dkfz.de/en/jobs/93782/… This job ad stays effective until the positions are filled. Please send your applications to [email protected]

Cool study! Congrats Chenqi! sciencedirect.com/science/articl…

Super excited to share with you are our newest paper on cBAF regulating CD8+ T cell fates and long-term memory! Great collaboration with HargreavesLab and superstars Bryan McDonald, Brent Chick, Nasiha Ahmed! authors.elsevier.com/a/1hF443qNrUu3…

Exciting news! Beta-blockers could synergize with immunotherapies, even in tumors typically resistant to such therapies. Clinical trials are underway, offering hope in repurposing these medications. salk.edu/news-release/r… Cancer Research Institute DFG public | @[email protected] AACR @AAI #NOMIS Foundation

It started from 2015 before I established my lab. I was writing a Roche pRes grant when I was doing revision of my last study as a postdoc. Based on the generous support, we can recruit and work with @MathiasWenes and Alison Jaccard . It a great effort from them.

So happy to share a new study from our group DKFZ HI-TRON Mainz rdcu.be/dn8d9 We found that the malate shuttle enzyme Got1 catalyzes an atypical chemical reaction in exhausted CD8 T cells.

So happy to share a new study from our lab: serine enrichment in the tumor microenvironment (TME) driving Treg cell differentiation. 1/3 science.org/doi/10.1126/sc…

We measured >600 metabolites in the TME and found serine was enriched (data in supplement table 1, may be useful for colleagues in the field). The serine-sphinganine-Fos axis pushes Treg cell differentiation. 2/3 science.org/doi/10.1126/sc…

My lab at USTC is recruiting postdoc fellows （jcyx.ustc.edu.cn/2024/0315/c244…）. Join us to study the mysteries of the TME! 3/3 science.org/doi/10.1126/sc…

Excited to share our 1st TCR-T therapy study with Drs. Haopeng Wang and Jizhong Lou, published in Cell Chemical Biology: Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity! cell.com/cell-chemical-…

A new study led by @marvinhering: sphinganine serves as a checkpoint for macrophage pattern recognition in sepsis and melanoma. nature.com/articles/s4146…

Li, Møller, Ho et al. Université de Lausanne show how tumor-derived lipids can induce an IL-6–dependent increased glutamine synthesis pathway in cancer-associated fibroblasts, supporting CAFs ability to promote pro-tumorigenic tumor-associated macrophages. hubs.la/Q03xvmfr0