Check out SPORT - a computational protein design strategy for making split proteins work for you! Northwestern CSB Northwestern Engineering @VatsanRaman UW–Madison @NatureChemBio nature.com/articles/s4158…

Our new study on predictive design of mammalian genetic programs is out in Science Advances! We paired engineered genetic parts that have special capabilities with computational models to design circuits that perform sophisticated, useful functions advances.sciencemag.org/content/7/8/ea…

Thanks NIBIB for highlighting this cool project led by Joe Muldoon with Bagheri Lab Northwestern CSB nibib.nih.gov/news-events/ne…

Happy to share our new review on the power of using process control concepts to understand and build genetic programs in mammalian cells by @dray_kate Hailey Edelstein Katie Dreyer (she/her) Northwestern Engineering Northwestern CSB sciencedirect.com/science/articl…

Very psyched to see this paper out in the world - it is the review we wish existed! Hope this is as much fun to read as it was to write with Leonardo Morsut, Hailey Edelstein, and Janvie Manhas with great input from Terry Sheppard from Nature Chemical Biology

I’m so proud to see this review finally out! The synthetic receptor space is evolving quickly and capturing that development here was all around fun! Thanks to my co-authors for all of the brainstorms and teamwork. It’s been a blast! Janvie Manhas Josh Leonard Leonardo Morsut

Happy to share that our study on engineering nanoscale decoys to fight COVID-19 is now published! A big thank you to the team for your hard work, advice, & mentorship! (Josh Leonard Kamat Lab Devin Stranford Roxi Mitrut )

Check out a fun new perspective on super-cool recent work by ElowitzLab, Richard Murray and team in GEN Biotechnology (with Hailey Edelstein and Gauri Bora ) liebertpub.com/doi/10.1089/ge…

I’m thrilled to introduce a story that has been many years in the making – the GEMINI platform for engineering multifunctional extracellular vesicles as versatile, programmable, biological delivery vehicles biorxiv.org/content/10.110…

We’re thrilled to be selected by AbbVie for their 2022 AIM award! Great work team! Josh Leonard Jay Rosanelli Devin Stranford Hailey Edelstein

Hello darkness my old friend...Have you ever had your transgene or synthetic gene circuit silence? Check out this awesome collaborative review by many leaders in mammalian synbio. sciencedirect.com/science/articl…

Have you ever wondered how to improve loading of protein cargo into extracellular vesicles? Excited to share our latest work exploring how lipid-protein interactions may be leveraged to direct proteins into extracellular vesicles! tinyurl.com/45sdm55m 🧵 1/6

What a fun collaboration with Kamat Lab & Institute for Protein Design led by Justin Peruzzi & Taylor Gunnels - dig in for some fascinating EV science and useful EV bioengineering tools that we are thrilled to share

VERY excited to welcome this paper out in Nature Biomedical Engineering where we introduce the GEMINI platform for engineering multifunctional extracellular vesicles as versatile, programmable, biological delivery vehicles nature.com/articles/s4155…

Red blood cells have some wildly cool capabilities – what if we could engineer them to work as living diagnostics? Check out this exciting first step (led by Taylor Dolberg & Taylor Gunnels): biorxiv.org/content/10.110…

I’m thrilled to finally share this work from the Leonard lab and grateful for a fantastic team, especially my coauthor Amparo!

Excited to share our work Nature Communications on biomembranes, lipid rafts, drug delivery, and extracellular vesicles (EVs). We used lipid-protein interactions to control protein trafficking and improve functional delivery of transcription factors > 50X! tinyurl.com/ycprfywe (1/8)

Thank you to Northwestern Engineering for covering our paper! mccormick.northwestern.edu/news/articles/…

A new study by Lurie Cancer Center member Joshua Leonard, PhD, could ultimately enable the development of safer and more effective treatments for #cancer using ‘smart’ cell therapies." spr.ly/6019f2Yfv Josh Leonard Northwestern CSB Northwestern Engineering Hailey Edelstein Amparo