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Check out latest from the Walter-Pellman collaboration, revealing how the replisome is remodeled in mitosis to allow CMG eviction, which we propose minimizes fallout from under-replication. biorxiv.org/content/10.110…

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How does ATP hydrolysis by MCM enable replicative helicase loading onto DNA? Find the answer in our latest article rdcu.be/d6D8D Congratulations to Agata Butryn, who spearheaded the entire project, Contributions from Julia Greiwe in the early days. 🎉❄️🔬🧬

ProtGPS, a protein language model, cracked cellular localization code of human proteins, predicting their destination and finding pathogenic mutations that disrupt localization. Kudos to scores of wet lab biologists whose real-world data made this possible science.org/doi/10.1126/sc…

Happy to see this work out 💪A great collaboration with Krejci lab (LORD). Congratulations to all authors! 👏 Read the full story here: nature.com/articles/s4146…

Proteogenomic analysis of evolved aneuploid cell lines & primary tumors reveals adaptive strategies for alleviating the consequences of aneuploidy in cancer – including increased expression of DNA replication and repair factors Zuzana Storchova and coworkers embopress.org/doi/full/10.10…

Thrilled to share our latest work in nature! We show how cancer cells navigate DNA replication despite DNA damage, revealing new insights into genome stability. Huge thanks to my incredible collaborators! Check it out here: nature.com/articles/s4158…

Thrilled to share our lab's first preprint, led by an exceptional PhD student GITA CHHETRI and with the support of wonderful collaborators, we find that replisome function is rate-limited by strand-specific PCNA dynamics. biorxiv.org/content/10.110… A teaser:

Our new preprint is now on bioRxiv! 📄 We introduce qAID, an AI-based workflow for automated analysis of DNA replication dynamics. Glad to have contributed a small part to this study.

Hey everyone! If you are interested in the world of DNA replication dynamics and if you use DNA spreading or combing assay 🧬, read this great preprint on how to save time spent on microscopy🔬 and fiber analysis 📊 Thanks for letting me be a part of it! 🥼 I am honoured.

Truly honored that my career path and laboratory have been featured in the 'Cell Scientist to Watch' interview series. A huge thank you Sara Morais da Silva and J Cell Science for this wonderful opportunity 🙏