
Hazem Ibrahim
@hazemibrahimi
Postdoctoral Researcher @OtonkoskiL @Helsinkiuni utilizing CRISPR tools and human stem cells to create diabetes models and to study β-cells (views are my own)
ID: 953902723778465792
18-01-2018 08:11:46
357 Tweet
612 Followers
1,1K Following





Uusi kuvantamismenetelmä diabeteksen soluhoitojen tehon ja turvallisuuden tutkimiseen. Menetelmän avulla voidaan määrittää siirteiden kokoa ja laatua, mikä parantaa diabeteksen solukorvaushoitojen turvallisuutta ja tehokkuutta. Medicine and Health, University of Helsinki Turun yliopisto - University of Turku helsinki.fi/fi/uutiset/ela…

The RFX6 gene mutation impairs insulin secretion and increases the risk of type 2 and gestational diabetes. University of Helsinki Hazem Ibrahim OtonkoskiLab helsinki.fi/en/news/diabet…






Kudos to Hossam Montaser for exploring the diabetes phenotype in MEDS1 syndrome (Microcephaly, Epilepsy, and Diabetes Syndrome-1)! doi.org/10.2337/db24-0… Our previous work on MEDS2 (doi.org/10.1172/JCI141…) found a similar phenotype, though with much less mechanistic detail.


📢New human fetal pancreatic organoid model generates all three key cell types of the pancreas. New paper in Cell by Amanda Andersson Rolf , Hans Clevers and collaborators. See the article here: sciencedirect.com/science/articl…



The postsynaptic density in excitatory #synapses is composed of clustered, heterogeneous nanoblocks. New study from Rong Sun, Qiangjun Zhou Zhou_Lab-Vanderbilt and colleagues Vanderbilt Center for Structural Biology Vanderbilt University: hubs.la/Q03dGgPD0 #Biophysics #Membrane #lipid #Neuroscience #CryoET


Excited to share our new research on the metabolic maturation of stem-cell-derived islets upon murine engraftement. Published today in Diabetologia: link.springer.com/article/10.100… OtonkoskiLab Timo Otonkoski Katajisto Lab MetaStem University of Helsinki #SCislet #betacell #diabetes
