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Proudly presenting the peer-reviewed version of our manuscript “ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics” in @Genome Biology #ACME #SingleCell genomebiology.biomedcentral.com/articles/10.11… A thread (1/12) 👇

Check out our paper on near complete correction of a muscular dystrophy causing mutation in primary human muscle stem cells by base editing!

🥼 Scientists at Max Delbrück Center show that autologous gene repaired human muscle stem cells can be harnessed for cell replacement therapies of #MuscularDystrophies. bit.ly/32cS5G8

Researchers at the ECRC, a joint entity of the #mdcBerlin and Charité - Universitätsmedizin Berlin, have developed a new gene-editing technique that could lead to the first potential cell therapy for genetic muscle disorders. The team now explained its findings in JCI insight: mdc-berlin.de/news/press/mil…

Very happy about our cover on JCI Insight!

#Epispadie führt zu lebenslanger Inkontinenz. Kann #Stammzell-Transplantation helfen? Ein Team um @SimoneSpuler (Charité - Universitätsmedizin Berlin) führt klinische Studie durch, gefördert von @BMBF_Bund und @berlinnovation. HealthCapital Berlin-Brandenburg Research in Germany - Initiative of the BMFTR #braincityberlin mdc-berlin.de/de/news/press/…

In the video, @SimoneSpuler and lead author Helena Escobar Fernandez now give insight into the study JCI insight: youtube.com/watch?v=AgNlm9…

Please RT. We are hiring!! computational #postdoc in #singlecell transcriptomics in #Barcelona IDIBELL Programa de Medicina Regenerativa de Catalunya Deadline of applications 13th june. More info 👇idibell.cat/es/ofertes-fei…

Happy to share our latest study on using mRNA to deliver CRISPR tools to human muscle stem cells ex vivo, achieving very efficient gene and base editing in a single, selection-free step!

From Max Delbrück Center researchers in @moltherapy Nucleic Acids (#MTNA): #mRNA-mediated delivery of #geneediting tools to human primary muscle #stemcells cell.com/molecular-ther…

Wowww enhorabuena Diego y equipo!

Are you looking for #PostDoc opportunities in #singlecell in Barcelona? In my lab we are looking for candidates to apply for a Beatriu de Pinós fellowship to use scRNA-seq to study neurodegenerative diseases. DM if you are interested. agaur.gencat.cat/en/beques-i-aj…

And Silvia Di Francescantonio !

We are looking for a highly motivated #PhD #candidate to work on Unveiling an unprecedented function of 3-O-sulfated heparans in the cell nucleus and its importance for #myogenesis. Applicants should contact us on [email protected] at latest by early next week! Pls RT!

Very happy to have our work featured on the cover of Mol Ther - Nucleic Acids. Beautiful image by Silvia Di Francescantonio. mRNA-mediated delivery of CRISPR tools to edit human muscle stem cells. @SimoneSpuler @ChrisStadelmann. Max Delbrück Center Molecular Therapy

A #CRISPR therapy for muscular dystrophy developed at #mdcBerlin and Charité - Universitätsmedizin Berlin is showing promise in mice. The study was published in Nature Communications. mdc-berlin.de/news/press/dev…