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Bacteria produce chemical compounds that humans harness as drugs (ex antibiotic). We hypothesize that a major biological role of these compounds have been overlooked: antiviral defense. 👇Discovery of lantiphages, a large BGC family wt antiphage function biorxiv.org/content/10.110…

Modified peptides produced by bacteria protect from phage infection - congrats Helena Shomar and Aude Bernheim for this fantastic discovery! Can these new antiviral molecules also inhibit viruses that infect humans? 🤔

A new kid on the block of "chemical defense" against phage infection. Helena Shomar reports on the antiphage activity of lanthipeptides. Remembering early discussion in Portugal and now looking forward to reading your beautiful work! New Concepts in Prokaryotic Virus-Host Interaction

Paper out today: “RNA-guided RNA Silencing by an Asgard archaeal Argonaute”. A wonderful, multidisciplinary project co-led with Daan C. Swarts Joo_Lab, spearheaded by Carolien Bastiaanssen Pilar B U Kijun Kim @FinocchioGiada & Yanlei Feng. nature.com/articles/s4146… Nature Communications

Viperin immunity evolved across the tree of life through serial innovations on a conserved scaffold rdcu.be/dMJJd

Yasmine Belkaid, directrice générale de l’Institut Pasteur : « Aujourd’hui, j’ai peur de perdre ce qui m’a fait choisir la France » lemonde.fr/idees/article/… via Le Monde

What a week!🥳 Our work describing the functional and evolutionary history of viperins is finally out! We describe how this ancient immune gene was conserved and diversified across the tree of life ! Hope you enjoy the final version of the manuscript 😀

Scientists in France have expressed relief that the right-wing party National Rally was defeated in yesterday’s parliamentary elections go.nature.com/3xROocr

Together with Aude Bernheim we wrote a research briefing: "Evolutionary history of an immune protein conserved across all domains of life" nature.com/articles/s4155… Link PDF: rdcu.be/dM5fY We describe our findings recently published in NatureEcoEvo : nature.com/articles/s4155…

1/ 🧵 Thrilled to share work of Eligo Bioscience just published in nature ! We show proof of principle results of efficient base editing performed on E. coli directly in the mouse gut 🦠💡 #Microbiome #SyntheticBiology nature.com/articles/s4158…

After a high dose of psilocybin, the brain desynchronizes at a massive scale, causing loss of our sense of self, time, and space. This may drive the burst of plasticity caused by psychedelics. The next day, brain activity has largely returned to normal, but an echo remains – a

My cat Shouka came to the lab for his monthly meeting to help us with BGC refactoring #NaturalProductsCat

Me !!!! 🙋‍♀️

Two years ago we published the discovery of hotspots of novel anti-phage defense systems in the genome of P4 phage satellites, including a mysterious Phage Anti-Restriction Induced System (PARIS). We have now published the mechanism in nature nature.com/articles/s4158…

AMAZING ! Well deserved!!!! David and Demis have been my personal Beyonce and Rihanna for years 🤩🤩🤩