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Big congratulations to 🎗️Karina Yaniv🎗️, GrauperaLab, and valentina greco on being awarded the European Research Council (ERC) Synergy Grant "Decoding endothelial cell behavioral mosaicism within single vessels". So well deserved. Angioscience is rocking!!!

Congratulations to Anna Dimberg, Magnus Essand and Thomas Tueting on being awarded the European Research Council (ERC) Synergy Grant "Targeting the vascular-immune interface to induce anti-tumor immunity". Fantastic recognition for outstanding VB research! Well done!!!

Of the 191 lucky ERC SyG awardees, 12 (6.3%) are from the US, i.e., European taxpayer money supports research in the US. While I greatly support the openness of the ERC to promote international collaboration, I wish US funding agency were similarly supportive of European science!

Congratulations to Bong-Ihn 'the apple does not fall far from the tree' Koh (Bong-Ihn Koh) & Vishal Mohanakrishnan (Vishal Mohanakrishnan) from the Ralf H. Adams lab for their landmark bone vasculature papers in nature (nature.com/articles/s4158…) & Nature Cell Biology (nature.com/articles/s4155…)

Interesting immunooncology postdoctoral position in the laboratory of Gabriele Bergers {BergersLab) at CCB_VIB_KUL.

Congratulations Mahak for the acceptance of your first last author paper as independent PI! I am sure there is more to come soon. Happy to see you among the strong and growing next generation of angioscience researchers.

7/Epigenetic states define disseminated tumor cell (DTC) fate. In this study, the authors find that hypomethylated DTCs respond to WNT ligands, extravasate and undergo dormancy, while methylated DTCs proliferate intravascularly. Moritz Jakab Hellmut Augustin nature.com/articles/s4301…

Want to know how to isolate liver endothelial cells without any prior training? Check our latest work in @CommsBiol, describing a high-throughput perfusion-independent method to isolate liver sinusoidal endothelial cells. Blood vessels rock!!! EVBO rdcu.be/d5C82

Congratulations to Charlie Dalin for winning the 2024/25 Vendée Globe single-handed round the world sailing race in an all-time record time of less than 65 days. Spectacular accomplishment. Fingers crossed for Boris Herrmann (10th place) for the remaining 3.000 mile finish line.

Epigenetic regulation of placental vascularization – now published in Developmental Cell (sciencedirect.com/science/articl…). Congratulations and thanks to Stephanie Gehrs for fantastic work and paving the way of the augustinlab.de into the world of vascular epigenetics. There’s more to come!

Online now: The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms dlvr.it/THMCSS

Spectacular hemangioma work from Joyce Bischoff lab in Journal of Clinical Investigation. Fantastic basic science (discovery of SOX18-mevalonate pathway in hemangioma) combined with great translational perspective (drug repurposing). Congrats to Anne Holm! Check it out: dm5migu4zj3pb.cloudfront.net/manuscripts/17….

Angiocrine signaling is rocking - pericrine signaling is the new kid on the block: Hepatic stellate cells control liver function (‘HSCs make the liver great again’) – now published nature (nature.com/articles/s4158…). Fantastic collaboration with the Robert Schwabe lab Columbia Univ.

Gratifying to now see our pericrine liver work in the print version of nature (nature.com/articles/s4158…). Massive piece of work with 651 display items (174 main, 477 supplement). Feels like we are publishing books and not papers. Thanks to Robert Schwabe for great collaboration!

Another hyped study in Nature Medicine claiming to have developed a predictive test for the identification of women at risk of developing preeclampsia. Sobering: The predictive value is no better than the cheap routine measurement of sICAM & sVCAM reported more than 20 years ago.

Don Nguyen, PhD (center) chaired an Education Session #AACR25 on Non-Genetic Drivers of Cancer Metastasis featuring Hellmut Augustin and Ashley Laughney. AACR Yale Pathology Smilow Cancer Hospital

Following our epigenetic placental vasculature paper Developmental Cell (sciencedirect.com/science/articl…), the second chapter of our forthcoming vascular epigenetic trilogy was now published in Nucleic Acids Res (academic.oup.com/nar/article/53…): DNMT3A regulation of endothelial enhancer landscape. More to come!

Spread the word: The European Center for Angioscience Uni Heidelberg continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in nature: nature.com/naturecareers/…