CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density: Neuron cell.com/neuron/fulltex…

Thrilled to share my first first-author paper is out in Neuron! We show that Alzheimer's disease protective CLU alleles upregulate CLU in response to neuropathology, dampening inflammatory signaling between microglia and astrocytes. Read here sciencedirect.com/science/articl…

New TYP lab paper out today in Neuron led by PhD student Alex Lish! We took a deep dive into the mechanisms underlying CLU in AD using innovative iPSC, mouse, and human data approaches. Be sure to give it a read! cell.com/neuron/abstrac…

🚀 BrightFocus is fueling the future of science. Today, we announced that we’re investing nearly $13 million in 50 bold new research projects to fight Alzheimer’s, macular degeneration, and glaucoma. These groundbreaking studies span 10 countries and focus on earlier detection,

Honored to be a recipient of a research fellowship from BrightFocus Foundation!

TYP-ers attended the BIGG meeting at UMass on Monday, and had a great time presenting talks and posters! PhD student Gizem Terzioğlu & postdoc Kellie gave amazing short talks, Master's student Emma Karp & postdoc Sarah Heuer, PhD got great poster traffic!

Emma has become such an impactful member of the lab and will truly be missed!! Big things ahead for this young neuroscientist!

With the generous support of Frank Ondrey, MD, PhD, the RADC is pleased to present the Martha Ondrey Graduate Student Prize to Tain Luquez, MPhil. Luquez presented research on multi-doman cognitive resilience to Alzheimer’s Disease and TDP-43 neuropathologies. #ROSMAP2025

Shoutout to our lab at the ROSMAP meeting! Thanks David and the great team at Rush Alzheimer's Disease Center for a great meeting! 🎉 Sarah Heuer, PhD gave a great talk & won the Martha Ondrey Jr. Investigator Award 🏆 🧠 Gizem Terzioğlu crushed it with her presentation on SHIP1 & the inflammasome!

And that concludes RADC #ROSMAP2025. On behalf of Dr. David Bennett, faculty and the entire RADC staff, we thank all presenters and attendees for a most engaging conference. Until next time! Safe travels!

📢 Check out this new nature study! .Fran Quintana Lab and collaborators establish that IL-11–STAT3-driven #astrocytes suppress #glioblastoma-specific protective immunity by inducing TRAIL-dependent T cell apoptosis. 👉 go.nature.com/3F3NyNt

Honored to have been awarded the Martha Ondrey Postdoctoral Prize and share my work at the annual ROSMAP meeting this year! Thank you to Rush Alzheimer's Disease Center for the award and hosting a fantastic meeting!

Huge congrats to our Master’s student Emma Karp for receiving the GBM Master Prize from the Society for Biochemistry and Molecular Biology! 🏆🧬 Emma earned it for her work in Biomedical Neurosciences at TUM! 🎓🧠 🔗 gbm-online.de/de/studium-kar…

New TYP lab publication led by PhD student Alex Lish out today in Cell Reports! We present a reproducible neuron-astrocyte-microglia tri-culture model to study intercellular interactions in Alzheimer's disease. Read more here: cell.com/cell-reports/f…

Highlights from our lab at the Keystone Symposia Neurodegeneration meeting! Sarah Heuer, PhD delivered an excellent talk on ABCA7 loss and microglial dysfunction in Alzheimer’s! Alex Lish presented a great poster on CLU and intercellular communication in Alzheimer’s!

🧠 New study in Brain, led by graduate student Courtney Benoit, uncovers how the autism-linked gene POU3F2 supports brain development by promoting neural stem cell growth via Wnt signaling and key targets like ADNP and SOX13 academic.oup.com/brain/advance-…

Huge shoutout to our brilliant graduate student Gizem Terzioğlu for delivering a great HMS Neurobiology Pizza Talk! 🍕🧠 She highlighted exciting insights into how SHIP1 shapes microglial function at the intersection of intracellular trafficking and immune response.

"No one’s Ph.D. journey is the same, and no one deserves to be shamed for how long it takes." #ScienceMagArchives scim.ag/3PjwJzf

Huge congrats to Zack Murphy, selected as a 2025 Fujifilm Fellow at Harvard Medical School !! 🎉 The Fujifilm Fellowship Program fully funds PhD students doing groundbreaking work in the life sciences! Look out for big things ahead from Zack!

Thank you IU School of Medicine for this lovely profile of me. IU School of Medicine IU Neurology Stark Neurosciences Research Institute have been so welcoming and open to my ideas and vision in establishing the Center. Moving my lab here two years ago was the best decision ever made! medicine.iu.edu/blogs/neurosci…