
Hijai Regina Shin
@hijaishin
Hijai R.Shin in publications. PhD @SeoulNatlUni, Postdoc @berkeleymcb, Assistant professor @CRI_UTSW. Interested in #autophagy #lysosome, metabolism, cancer.
ID: 1041784735201030144
https://scholar.google.com/citations?user=dQxXEV4AAAAJ&hl=en 17-09-2018 20:23:31
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Chris Lupton and myself as equal co-first authors, study co-led by @Dr_Ellisdon and Dr Michelle L Halls. Monash University Monash Biomedicine Discovery Institute Monash Medicine, Nursing and Health Sciences Monash Research Monash Institute of Pharmaceutical Sciences University of Sydney

Spectacular cryoEM structure of LYCHOS by Charles Bayly-Jones & team out in @nature strongly supports its role as cholesterol sensor for mTORC1 that we (Hijai Regina Shin) discovered, and points to an intriguing mechanism of transport-coupled cholesterol binding. Congratulations!

We are excited to host the incredible Rushika M. Perera at Children’s Research Institute at UT Southwestern! Don't miss her talk on 'Metabolic Dependencies of Metastatic Pancreatic Cancer' this Thursday, Nov 14, from 12–1 pm at NL 12.125.




I am beyond thrilled to become a Searle Scholar! Thank you Children’s Research Institute at UT Southwestern, Sean Morrison @RalphDeBerardinis (no longer on X), Roberto Zoncu for all your support and mentorship!

Genetically encoded tool for manipulation of ΔΨm identifies its role as the driver of ISR induced by ATP synthase dysfunction by Mangyu Choe, Denis Titov et al at UC Berkeley dlvr.it/TKF1SB


Excited to share our lab's new paper led by Mangyu Choe where we co-opt UCP as a genetically encoded tool for manipulation of mitochondrial membrane potential. We use this to demonstrate that high ΔΨm drives integrative stress response in response ATP synthase inhibition... 1/2

Very nice work by Denis Titov and Mangyu Choe. I’m so glad this is finally out and that our lab contributed to the story 🥰

Excited to share the N&V Roberto Zoncu and I wrote for NatureStructMolBiol on the recent surge of LYCHOS structure papers! 🚀 We propose a unifying model that ties together these new discoveries. It’s incredible to see so much momentum building on our work. nature.com/articles/s4159…

