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After a pandemic hiatus, BhabhaEkiertLab and I are pleased to organize the next iteration of the NY Area cryo-EM meeting, April 19, 2023 at Rockefeller! See details in the flyer below. Please RT, and apply if you are interested: forms.gle/k6kG9ShC8DKej5…

Congratulations Steve Brohawn and David Kern on the new story! Really exciting to how much you have been able to learn about the heteromeric channels and their regulation by lipids.

Exciting work from Tim Kenny and Kivanc Birsoy identifying FLVCR1 as a mammalian choline transporter! Congratulations to everyone involved in this fun project!

Congratulations James! Well deserved.

Authors from Memorial Sloan Kettering Cancer Center: Hite Lab, @labnavid and @VinaySapuru report structures of IP3 receptor with insights into the biphasic dependence on Ca2+ for channel activity. nature.com/articles/s4146…

Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 @nature rdcu.be/dGpw6 Congratulations Hite Lab Memorial Sloan Kettering Cancer Center!! My favorite part: residues specifying Etn vs Cho uptake. Potential clues for evolution of nutrient uptake programs?

Excited to share our study on a high-affinity choline and ethanolamine transporter, FLVCR1, published today at Nature. I am grateful for my doctoral advisor ,Hite Lab , my co-authors and collaborators, Tim Kenny, Artem Khan, and Kivanc Birsoy. doi.org/10.1038/s41586…

Nature research paper: Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 go.nature.com/4dpuKEH

Our collaboration with Will Pipatpolkai on NOX5 is out. We captured NOX5 in different activation states, and used MD simulation to explore the initiation of electron transfer. An unexpected Zn finger was also identified that is critical for function. nature.com/articles/s4146…

Very grateful that I am invited to give a webinar for ASBMB Lipid Research Division on May 29th, 12-1pm EST. You can register to attend the webinar via the ASBMB website below. Looking forward to meet and discuss research with everyone! asbmb.org/meetings-event…

Our newest preprint identifies a role for p53 in balancing nutrient supply and demand by enabling phospholipid headgroup recycling 1/

Very grateful to give a webinar for BRIC on June 18th Tuesday, 11am KST (or June 17th Monday 10pm EST!) about my recent work on the high-affinity choline and ethanolamine transporter, FLVCR1. ibric.org/bric/webinar/a…

New work from our lab’s genomics guru Artem Khan with Eric R. Gamazon. Artem generated a new platform for metabolic gene discovery and identified the mitochondrial choline transporter. Rockefeller University Nature Genetics nature.com/articles/s4158…

Metabolic regulation of the hallmarks of stem cell biology by Jackson (Benjamin Jackson) and Finley (Lydia Finley) hubs.li/Q02JJ03D0 Collection highlight from Cell Stem Cell

Our work on human urate transporter is out Cell Research. Y. Dai single-handedly drove this project, which revealed the transport and drug mechanism of URAT1. We are grateful for the tremendous support from Structural Biology at St. Jude Children's Hospital nature.com/articles/s4142…

OK, I’ll bite. We, as scientists, believe our work has value to society. Enough value that we ask for funding from taxpayers and philanthropists. We should be able to justify this value.