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How do mesodermal cells find their way during gastrulation? During my PhD in the @PauliGroup at the IMP we found a self-generated Toddler gradient mediating directed cell migration. So thrilled to see my work published in Science Advances. (1/12) science.org/doi/10.1126/sc…

Preparations in place for our big reunion tomorrow to celebrate the *20 years of Heisenberg Lab* 🤩🤩 We are so excited to have a meeting of current members, alumni and friends from all around the world! Follow this space and our hashtag #20yearsofheisenberg for more.

We started the first day of #20yearsofheisenberg with a lot of catching up and great talks! 🧵

People are asking me about the origins of and key milestones in the timeline of #bioorthogonal chemistry, so here is a quick summary. 1/n

Super happy to see it out!! Nodal/TGFb morphogen gradient encodes both motility-driven unjamming and a code of heterotypic adhesion in gastrulation => collective and ordered mode of migration that reshapes embryos while preserving patterning! See 🧵 below nature.com/articles/s4156…

Keeping the spirits high when the servers are down: 🍕✅🔬❎

Our paper on dormant egg ribosomes is out now! I couldn't be more grateful to work with Laura Lorenzo-Orts,@PauliGroup Haselbach lab and so many others. I learned so much and discovered my passion for #ribosomes nature.com/articles/s4158… Thank you for your enthusiasm and support!

Our #SpotlightZebrafish this week is on Dr. Tushna Kapoor Tushna Kapoor, a postdoc w/ @HeisenbergCPlab ISTAustria. She investigates mechanisms of surface layer spreading in zebrafish embryos and how actin networks in different tissues orchestrate embryo-scale morphogenesis (1/2)

Exciting news! Our latest publication by karlahuljev et al. shows a hydraulic feedback loop that promotes embryonic axis formation in #zebrafish. Check our tweetorial for a sneak peek. Developmental Cell: sciencedirect.com/science/articl…

Wenn Sie etwas über Ernährung und Sport, die Funktionsweise der Zelle und die Welt der RNA erfahren möchten, kommen Sie heute Abend zu den Vorträgen von Laura Hofmann, ISTAustria, @juliusbrennecke, IMBA imbavienna.bsky.social, Stephanie Ellis, Vienna BioCenter, molecular.sylvia, Vetmeduni!

🆕Exploring the world of oocyte maturation!🐟 Our latest work by Shayan Shamipour et al. shows a key role of yolk granule fusion and microtubule aster contraction in preparing the oocyte for fertilization! Read how below 🧵⬇️ PLOS Biology: plos.io/3oTs9hE

Today we had the second edition of the Heisenberg- Edouard Hannezo group joint lab meeting! We had an amazing line-up of talks, which will hopefully lead to many new collaborations 🤩 (1/2)

How do distant DNA loci come into contact to activate genes? Our paper combining live imaging 🔬& polymer physics 🧬 to answer this is out in Science Magazine! We show how chromosome packing & diffusion determine pairwise dynamics & transcription 👉science.org/doi/10.1126/sc… 1/n

📢 We are looking for a temporary, part- time technician to join our research group! 🐟🧬 Come be a part of our team ISTAustria, on the outskirts of Vienna 😊 All details below, please use the link to apply 👇 Please RT! ista.ac.at/en/job/?title=…

My postdoc work is out on bioRxiv biorxiv.org/content/10.110…! I want to thank all the co-authors (present in the Twitter world David Brückner Saren Taşçıyan 🇪🇺 🧬 🧫 🤖 XinT Alexandra Schauer ) and all the friends and colleagues in Heisenberg Lab and ISTAustria 🤩

How do embryos avoid inter-tissue mechanical conflicts? Check out our preprint on the cephalic furrow: doi.org/10.1101/2023.1… An awesome collaboration between Yu-Chiun Wang Lab RIKEN BDR, and the Lemke lab @COSHeidelberg lead by Bipasha Dey, Girish Kale, and myself. A 🧵

After a very fruitful revision Current Biology, I am excited to present the final version of our paper at the end of the year🎄 Heisenberg Lab @nartimsoole Edouard Hannezo cell.com/current-biolog…

My PhD work is finally out Nature Physics!! We looked at the interplay between the cortex and cytoplasmic components to explore the role of friction forces in cellular morphogenesis. Many thanks to Heisenberg Lab, Raphaël Voituriez and Andrew Callan-Jones A thread (1/6)

📢Exciting new work from the lab by Nikhil Mishra et al, now out on bioRxiv, reveals that the early embryo geometry spatiotemporally patterns zygotic genome activation (ZGA) in zebrafish.🐟 tinyurl.com/Biorxiv-nmishra Have we piqued your interest? Read on to learn more... 👇

📢‼️The next preprint for your reading list is already here😉Latest work by our PhD student Suyash Naik on the cytoskeletal crosstalk required for efficient epithelial spreading that enables #epiboly movements in #zebrafish, is now on bioRxiv 👇 tinyurl.com/tntnw2rm