Singapore scientists discover new peptide that contributes to "elegant mechanism" body has in place to prevent excessive, potentially tissue-damaging inflammation during infection, such as cytokine storms #dukenus bit.ly/2RZ9vo1 via Duke-NUS Medical School EurekAlert!

We are hiring! Postdocs interested in cool new mitochondrial peptides please see nature.com/naturecareers/…

Registrations are now open for AussieMit 2022! Secure your spot today for the meeting on 16-18 November, at the University of NSW, Sydney, Australia.

Cooperative assembly of the mitochondrial respiratory chain cell.com/trends/biochem…

Catch Bruno Bruno REVERSADE live on radio today discussing our recent work on mutations in the gene FOCAD that causes acute liver disease in children. Live on radio CNA938's Health Matters at 4:10pm Singapore time (9:10 am BST or 10:10 am CET) channelnewsasia.com/listen A*STAR Genome Institute of Singapore (A*STAR GIS)

In Journal of Experimental Medicine, Nadkarni, Chu, Lee, et al Lena Ho show that CARD8 #inflammasomes are activated by Coxsackie B3 protease-mediated cleavage. Knocking out CARD8 attenuates CVB3 propagation & dampens #inflammation in a cellular model of viral #myocarditis.bit.ly/3Ut2ash

Big roles for small peptides! I’m so excited to share my work in the Perrimon Lab on mitochondrial “Sloth” peptides 🦥🦥, out now in eLife - the journal, explanation thread below elifesciences.org/articles/82709 1/16

Working with a great team to organize Keystone Symposia #Microproteins: from Discovery to Applications! Abstract deadline is Nov 6th. Please submit your exciting work and join us in Beverly, MA, USA in Feb2025! keysym.us/KSMicroprotein… #KSMicroproteins25

Did you know that the fetal immune system can protect from congenital infection before birth? -Proud to share our study identifying protective functions of #microglia, contrasting the harmful early influence of #monocytes and primitive macrophages to #zika virus infection.

What are respiratory supercomplexes (SCs) doing? Our collaboration with Lena Ho shows that an extra large SC forms between complex I and complex III in a mouse model of complex III deficiency. SC-XL rescues the respiratory defect. sciencedirect.com/science/articl…

Ever wondered why we need respiratory supercomplexes? New findings from our lab, in collaboration with James A. Letts, show how a specialized supercomplex - the SC-XL - can help mitochondria overcome some respiratory defects & provide cardioprotective benefits. Studying

We’ve wrapped up another fantastic meeting, celebrating the achievements of our award winners & the successful conclusion of our Microproteins conference! Congrats to Carly Houghton, Juveriya Qamar Khan , & Achala SF Vitharanage. @tfmPhD @carvunis #keystonesymposia #keystoneawards

Just concluded the amazing 2025 Keystone meeting on Microproteins in Beverly, MA. Thank you Thomas Martinez and Anne-Ruxandra Carvunis for curating such an outstanding program. A special shout-out to Sarah Slavoff for an inspiring keynote lecture. SlavoffLab @carvunis @tfmPhD

Exciting opportunity for researchers passionate about #mitochondria. Join us at Duke-NUS Medical School to explore mitochondrial #microproteins in metabolic control. Use AI to uncover therapeutic targets for metabolic diseases from the microproteome. Mitochondria News nature.com/naturecareers/…

Cool study on how a mitochondrial microprotein regulates mt-RNA metabolism: Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma: Molecular Cell cell.com/molecular-cell…

First crispr screen by rockstar postdoc Jiemin Nah Lena Ho to uncover microproteins required for mitochondrial metabolism. #mitochondria #microproteins Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation: Molecular Cell