
Hollenstein group
@hollensteinlab
Our group focuses on generating modified aptamers and developing chemoenzymatic methods for the synthesis of chemically modified, therapeutic oligonucleotides
ID: 900698197563256832
https://research.pasteur.fr/en/team/bioorganic-chemistry-of-nucleic-acids/ 24-08-2017 12:35:59
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Selection of Plastic-Binding DNA Aptamers for Microplastics Detection (Juewen Liu and Co-Workers) Juewen Liu @uWaterlooChem the Water Institute #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/an…

New issue of CHIMIA is out today. Check out the highlights from the new Swiss Chemical Society division of Materials Chemistry (MatChem) with guest editors Maksym Kovalenko and Simon Boehme chimia.ch/chimia/index #MaterialsChemistry #Materials #SCS #OpenAccess Swiss Chemical Society


Glad to see our new J. Am. Chem. Soc. paper online on New Year Day! Using Sc3+, a visiting PhD student Jin Wang obtained an aptamer with different affinities and binding and dissociation kinetics to rare earth metals. Thanks Philip Johnson and Rahith for NMR! doi.org/10.1021/jacs.4…


And then the enantiomer of every other known antibiotic e.g. penicillin will be effective. Vaccines will work as well. A letter details these points: science.org/doi/10.1126/sc… #science #chirality #syntheticbiology #SciencePolicyForum Science Magazine Science News News Medical


A new paper from Claudia Höbartner and Universität Würzburg #UniWürzburg reports the crystal structures of the ribozyme SAMURI, revealing the mechanism of its methyltransferase activity and site-selectivity nature.com/articles/s4158…

Happy to share a short interview (in french) on the synthesis of RNA oligonucleotides. Thanks France Culture and Institut Pasteur, since 1887. radiofrance.fr/franceculture/…

Very happy to share our new preprint on the selection of COT-modified aptamers. Great work by undergraduate student Charlotte. Congrats to all! chemrxiv.org/engage/chemrxi… Stay tuned for the published version. Institut Pasteur, since 1887 Structural Biology-Chemistry at Institut Pasteur Julian Tanner CNRS Chimie


Be sure to read "Natural, modified and conjugated carbohydrates in nucleic acids" by Debashis Dhara, Laurence A. Mulard and Marcel Hollenstein Hollenstein group Read the #OpenAccess review here 👇 pubs.rsc.org/en/content/art…



ReNAissance : révolutionner les traitements antiviraux grâce à l’ARN messager 🤝 CNRS Chimie CNRS Bretagne et Pays de la Loire CNRS Ile-de-France Meudon 👉 buff.ly/EVQo0Y6



Very happy to share out new pre-print on the enzymatic GalNAc-labelling of oligonucleotides. Big congrats to undergraduate student Elisa and graduate student Pierre Nicolas Bizat ! chemrxiv.org/engage/chemrxi… Institut Pasteur, since 1887 CNRS Chimie
