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The December 1 issue won our cover contest! Congrats to the authors from 'Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors' Tushar Tomar Fausto Rodriguez Christine Pratilas MD #AACR21 bit.ly/3g7M1Hi

Happy PA day! I am so thankful for our amazing, talented, brilliant, and fun group of PAs Johns Hopkins Pathology. They truly keep our department running. Of note, we are hiring a PA and supervisor right now- so PAs please consider joining our awesome gross room! jobs.hopkinsmedicine.org

From the friday fellows conference: #meningioma in a patient who died following seizures. #neuropath

Nice look at a normal #pituitary gland. What do the pink cells produce, and what do the purple cells produce? #pathology #neuropath #PathTwitter #endocrinology

A brown #cornea due to copper deposition in Descemets and endothelium in a patient with #MGUS. Special stain for copper upper right, and IgG (faint staining) lower right. #eyepath

IDH‐mutant brainstem #gliomas in adolescent and young adult patients: Report of three cases and review of the literature #neuropath #braintumor Children's Hospital LA onlinelibrary.wiley.com/doi/10.1111/bp…

Happy Monday! Here's a cornea from a young patient with congenital glaucoma. PAS stain. What's the abnormality? What's the clinical name for this finding? #EyePath

From the friday fellows conference - a true "mixed glioma"! The same block had both astrocytic (left) and oligodendroglial (right) regions, with ATRX loss in the atrocytic resions and retained expression in the oligodendroglial ones (lower images). #astrocytoma #oligodendroglioma

Congratulations to our AP/NP resident/fellow Dr. Thomas Zaikos for winning the Diagnostic Slide Session O.T. Bailey-Helena Riggs Award at the annual AANP meeting last week! #AANP #neuropathology

75 yo man w a nodule on the eyebrow. A perfect example of this entity! Reply with your diagnosis then click link to see answer & amazing WSI digital slide of this case: kikoxp.com/posts/3708. #Pathology #dermpath #dermatology #dermatologia #dermtwitter

Molecular testing of #Glioblastoma for #BRAF mutations isn't always available due to cost of testing and #healthdisparities . With Dr. Manabu Natsumeda, we identified radiographic features in BRAF mutated glioma that might prompt molecular testing. link.springer.com/article/10.100…

This mitotically active OLIG2 positive cerebellar tumor in a young adult had mutations in IDH1 (p.R132C), ATRX, and TP53. Infratentorial IDH-mutant astrocytoma often show IDH1-R132C/G and IDH2-R172S/G mutations, and may represent a distinct subtype PMID: 32776277 #glioma

From the fellows conference: Cingulate infarct due to subfalcine herniation associated with a temporal lobe laceration after a fall.#neuropathology

.Johns Hopkins Medicine Johns Hopkins Pathology-led study finds #inflammation from #SARSCoV2 infection damages nasal nerves, weakens odor signals to brain & may be responsible for #COVID19 loss of smell. @cherrycyho JAMA Neurology hopkinsmedicine.org/news/newsroom/… via Hopkins Med News

Congratulations to Daniel Brat, MD, PhD for being inducted into the Johns Hopkins Society of Scholars! It is an extremely competitive group, and the honor is well deserved. #neuropathology

Amyloid‐beta is present in human lymph nodes and greatly enriched in those of the cervical region alz-journals.onlinelibrary.wiley.com/doi/10.1002/al… Congratulations Juan and David! This article was one of the most downloaded last year.

Bravo!

Monthly RAD-PATH correlation conf. 70 y/o M with mental status changes. DLBCL w/fxs of lymphomatoid granulomatosis #neuropath #radpathmatch