HossainLab
@hossainlab
ID: 1676072660877606913
04-07-2023 03:37:42
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Noncovalent Peptide Stapling Using Alpha-Methyl-l-Phenylalanine for α-Helical Peptidomimetics | Journal of the American Chemical Society The Florey Science at Melbourne University of Melbourne #Peptide #Stapling #Helical #Peptidomimetics pubs.acs.org/doi/10.1021/ja…
Alpha-methyl-L-Phe can be used to staple a single chain mimetic of H3 relaxin without post synthetic modifications! now live in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja… Funded by NHMRC Ideas Grants. Akhter Hossain Ross Bathgate The Florey HossainLab American Peptide Society AusPeptide European Peptide Society
🧬A cutting-edge discovery from The Florey's HossainLab has solved a long-standing problem in peptide based drug development - paving the way for new treatments in a range of conditions. Find out how our researchers solved the floppy peptide problem: florey.edu.au/news/2023/07/n… 👇
Congratulations to our talented first year PhD student Hongkang Wu for winning the best student presentation at the winter PUG symposium! Watch this space for more excellent work from Him!
We have been hard at work on relaxin 2 minimization and stabilization attempts, please check out our latest publication - Further Developments towards a Minimal Potent Derivative of Human Relaxin-2 in IJMS doi.org/10.3390/ijms24… The Florey
Earlier this year we published our work on lipidation of B7-33, our single chain H2 relaxin analogue; showing a dramatic improvement in stability and retained activity. check it out here: mdpi.com/1422-0067/24/7… The Florey