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We’re excited to welcome Vangeli Geshkovski Vangeli Geshkovski as a new postdoc in our lab! Vangeli brings strong expertise in epigenetics and gene regulation, and we look forward to exploring new directions together. Welcome aboard, Vangeli! The Sainsbury Laboratory

1/ Last week we had the pleasure to share our passion for plant biology at the #RoyalNorfolkShow 🌾🌽 Huge thanks to the STEMM Village and our TSL volunteers! Jennie Yang Kim Wood Shania Keh (Nani) Nick Desnoyer Hsuan Pai 白暄 Phon Green Shona Strachan Siyu Song Adeline Harant

2/ We used a poster about scale along with a giant tomato plant & aphid all designed by Hsuan Pai 白暄 to immerse kids into the world of plants and plant-pathogen interactions 🌿🦠 After meeting our giant aphid 🪲 they got to hunt the mini real-life versions on the tomato plant 🍅

I’m excited to share our latest preprint on the cell biology of plant hypersensitive cell death! 🌱💥 We used live-cell imaging to unravel what happens after resistosome activation—one of the least understood phases of plant immune responses. doi.org/10.1101/2025.0…

See you soon at #2025ISMPMI ✨🌱🧫🧫🔬

Thrilled to share our latest bioRxiv! This work started during my PhD and was finished together with Jogi Madhuprakash. We found a Phytophthora infestans L-shaped effector that bridges a host TOL protein to activated NLRs to suppress immunity! biorxiv.org/content/10.110… 1/15

Crepe paper MICROROSE-00 Can’t wait to complete (if there’s ever an end!) the collection 🪄

Kicking off #ISMPMI2025! My poster is P-441 (out of 442?) — hopefully last but not least! Drop by and chat with me about dual-profiling plant genes and their associated microbes using PHYTOMap! 🌿P-441 | Wed 16 Jul | 13.30-15.15 doi.org/10.5281/zenodo… #OpenMPMI

Don’t miss Pai’s poster on Wednesday at #2025ISMPMI! Also available on Zenodo: zenodo.org/records/158546… #OpenMPMI #OpenScience

Great to hear that the strain is useful for you. Thanks for sharing the excitement! Linden

Check out this wonderful story from Jogi Madhuprakash and Ben Seager! An L-shaped effector suppresses NRC activation by blocking resistosome assembly half way through!

The #Agrobacterium story is still unfolding. I am excited to share my recent research on cyclic dinucleotide regulation of #Agrobacteium secretion systems at #2025ISMPMI! 📍 Poster Session 1, P-154 (Jul 15)

First micro-rose to bloom at The Sainsbury Laboratory ! Progress slowed a bit with moving, but I’m back at it. First up: make the genetic color palette 🎨🧬

🚨New bioRxiv alert! We are thrilled to share our latest findings—building on our earlier work on suppressors of helper NLRs of NRC family—a Phytophthora infestans L-shaped effector captures resistosome assembly intermediates of tomato NRC3! biorxiv.org/content/10.110… 1/10

Our model: Once activated, dissociated NRC protomers assemble in a stepwise manner to form a full hexameric resistosome. AVRcap1b blocks this process, capturing NRC assembly intermediates and relocating them via the TOL-ESCRT pathway. Effector biology rocks! #EffectorWisdom 8/10

Nobori lab in Cologne #2025ISMPMI … and yes we only have tall people (no 😝)

Thrilled to share an aspect of my PhD project on the discovery and characterisation of a novel group of 'phosphorylated' effectors deployed by the rice blast fungus during infection. With Nick Talbot Frank Menke Neftaly Cruz Mireles The Sainsbury Laboratory #2025ISMPMI

Poster session coming! Come visit our PHYTOMap methodology + microbiome combo! P-315 by Siyu Song P-441 by Hsuan Pai 白暄 #2025ISMPMI Cologne

Graduation day for two of The Sainsbury Laboratory #Proteomics team members. Congratulations Markus Draeger PhD and Michael Agbodo MSc. Double #ProudSupervisor

Join us on August 13 for Localhost! 🦠 Peter Whidden will present Mote, an interactive ecosystem simulation with hundreds of thousands of organisms. His custom GPU physics engine models many simple behaviors at a massive scale, producing fascinating emergent phenomena. RSVP⬇️