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Please RT – #PhD IOCB Prague - Check 35 available #PhDprojects in 18 IOCB groups from CHEM, BIO, and PHYS clusters including Petr Beier🇨🇿🇪🇺🧪📝 Michal Hocek 🇨🇿 🇪🇺 🌍 🍷🧬🧪 Cahova Group of Chemical Biology Jan Konvalinka Lab Tomáš Pluskal IOCBioNMR labs: uochb.cz/en/call-for-ph…

Excellent science!

N-glycosylation caught responsible for modulating receptor-ligand interactions IOCB Prague biorxiv.org/content/10.110…

IOCBioNMR contribution to understanding the calcium sensing mechanism by the transmembrane segment of Bordetella adenylate cyclase toxin BBA #biomembranes. sciencedirect.com/science/articl…

CK2 regulatory role for LEDGF interactome confirmed!

Never used so many biophysical techniques in one project...from paramagnetic NMR through AUC and X-ray crystallography to mass spectrometry.

Tento čtvrtek budeme s Davidem Hokszou z Matematicko-fyzikální fakulta Univerzity Karlovy a Vaclav Veverka z IOCB Prague diskutovat v live stream (facebook.com/events/1475531…) o průlomu v predikci proteinové struktury a jeho důsledcích. Přidejdte se ! #AlphaFold #casp14 Univerzita Karlova

Our structural work in the new paper.

It's so exciting to follow the research progress on a protein that spent its early days in the NMR tube. DDI2 has an important role in proteostasis, as shown in vivo by our colleagues from Jan Konvalinka Lab IOCB Prague #proteasome #ubiquitin #immunity biorxiv.org/content/10.110…

. Scientific Reports (open) N-Glycosylation can selectively block or foster different receptor–ligand binding modes, Joni Vuorio, Jana Škerlová, Milan Fábry, Václav Veverka, Ilpo Vattulainen, Pavlína Řezáčová & Hector Martinez-Seara* IOCB Prague nature.com/articles/s4159… #NMRchat #NMR

With a careful experimental design, one round of selection can lead to functional deoxyribozymes. Excellent idea!

Stellar glowing DNAzyme from the #Curtislab IOCB Prague. Awaiting future exciting applications! Congratulations onlinelibrary.wiley.com/doi/abs/10.100…

Researchers led by H. Courtney Hodges BCMHouston & Vaclav Veverka IOCB Prague discovered how disordered protein interactions coordinate the assembly of proteins controlling gene expression. @sciencemagazine: science.org/doi/10.1126/sc… Full story: uochb.cz/en/news/366/st…

Katerina Cermakova, Jonas Demeulemeester (Jonas Demeulemeester) and Vanda Lux - you have done an amazing job - big respect! Great support from all co-authors! IOCB Prague BCMHouston KU Leuven Harvard Medical School Faculty of Science of Charles University Science Magazine: science.org/doi/10.1126/sc… uochb.cz/en/news/366/st…

What is Edward Curtis' IOCB Prague favorite place on earth? Find out on his #IntroducingAngewandte page onlinelibrary.wiley.com/doi/10.1002/an… x.com/angew_chem/sta…

Our awesome collaboration with Vaclav Veverka H. Courtney Hodges AdelmanLab zeger debyser Jonas Demeulemeester Pavel Srb Vanda Lux + many others was just published in Science, where we reveal new roles of unstructured protein in transcription. (1/8) science.org/doi/10.1126/sc…

We are looking for a PhD student to join our lab at IOCB Prague to study chromatin associated complexes. #structuralbiology #nmr #cryoem #transcription #epigenetics @iocbionmr uochb.cz/en/open-positi… instagram.com/p/ChsE3UfDw2C/…

Although we were not successful in resolving the central IDR from LEDGF bound to nucleosomal DNA using #cryoEM, we stumbled upon an unexpected H3K36 methylation-independent docking site for its PWWP domain. This story was just published in Nucleic Acids Res and is summarized by Eliš Ká

#research #structuralbiology #chromatin #LEDGF #cryoEM Multivalency of nucleosome recognition by LEDGF (Vaclav Veverka) - Nucleic Acids Res: academic.oup.com/nar/advance-ar… Eliš Ká IOCB Prague Faculty of Science of Charles University

Exploring unsettled biomolecular interactions with an NMR twist. A joint effort with the Obsil lab. IOCBioNMR nature.com/articles/s4146…