🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

From the prolific University of Liverpool team of Michael Schmid Ainhoa Mielgo et al, another paper dissecting mechanistic underpinnings driving #PancreaticCancer metastasis. The authors identify four subtypes of “metastasis associated fibroblasts” or MAFs, of which hepatic stellate cell derived

Now Online Targeted protein degradation: from mechanisms to clinic dlvr.it/T69vDr

Having a good time at #TPDFocus Centre for Targeted Protein Degradation at the welcome meeting the old CRUK Scotland Inst (Beatson) crew: Alice Wicks (she/her), Ilaria Puoti, David McGarry, Dominika - also #Brd4 is not detectable in the city #TPD

#TPDFocus symposium gala dinner and #Ceilidh with an amazing view 😍 Centre for Targeted Protein Degradation

We are seeking a great chemist to come and work with us and Bioascent as part of our new knowledge transfer partnership jobs.ac.uk/job/DHT622/kno… Centre for Targeted Protein Degradation BioAscent #TPD

No rest for TPD! After a busy start of the week we hope you can now relax and enjoy this month’s issue of the CeTPD Journal Club.

We are seeking a Scientist with research experience in organic synthesis and/or medicinal chemistry to join the drug discovery team based in the new Centre for Targeted Protein Degradation within Dundee's School of Life Sciences. buff.ly/3KnitDb

1/7 Matthias Mann Lab and Georg Wallmann Georg Wallmann are proud to announce alphaDIA, our open source, next generation DIA search engine. Check out the preprint bioRxiv biorxiv.org/content/10.110…

On 24 June "Biomarkers in Industry, Health and Disease" symposium organised by the Edinburgh Association of Mass Spectrometrists will take place in IGC in Edinburgh (see the picture for details). It is free to attend but booking required. Booking link: eventbrite.com/e/symposium-bi…

Are you working in #Clinical or translational research? Join Charles Swanton, Catherine Elliott, Andrew Tutt and Graham Cadwallader on 11 September to find out all about our clinical research vision & ask any questions you might have. Sign up now 👉 bit.ly/4bTJ1Yh The Crick |

A real pleasure and privilege to host Rapé Lab in Dundee Centre for Targeted Protein Degradation UoD Life Sciences MRC PPU co-hosted woth Yogesh Kulathu ! Here in the highlight of the visit: lunch with our students and postdocs. thanks Micha for visiting!

The #HUPOECR & Young Proteomics Investigators Club want to help elucidate the mystery of grant writing! ✍️ Join us on September 11 at 4PM GMT to hear from Dr. Mike MacCoss (@mjmaccoss), Dr. Rebekah Gundry (@Gundrylab), and Dr. Jesper Olsen (Jesper V. Olsen) 🔥 Register today for free: shorturl.at/ZSLDX

A Framework for Quality Control in Quantitative Proteomics pubs.acs.org/doi/10.1021/ac… --- #proteomics #prot-paper

Super excited to share our latest paper on a novel targeted protein degradation technology, now out in Cell. We introduce RING-Bait technology, an innovative approach to selectively target and degrade intracellular protein aggregates (1/7) cell.com/cell/fulltext/…

Quality Control in the Mass Spectrometry Proteomics Core: A Practical Primer · Journal of Biomolecular Techniques jbt.pubpub.org/pub/fid694bn/r… --- #proteomics #prot-paper

ASP3082 KRAS G12D PROTAC Preliminary data of dose escalation 👉 Low grade AEs mostly rash and IRR 👉 ORR 18.5% in PDAC, DCR 48.1% 👉 ORR 23.1% in NSCLC, DCR 84.3% Combination ongoing in CRC #ESMO24 #ESMO2024

Online now! #Perspective Next steps for targeted protein degradation by Mackenzie W. Krone and Craig Crews at Yale University Yale Chemistry Department of MCDB dlvr.it/TG1Vz2

Funded PhD studentship available to start in Sep '25 working as part of a collab between our lab Centre for Targeted Protein Degradation, Prof Kev Read Drug Discovery Unit and Promega Corporation aiming to establish assays and design rules for induced proximity molecule efflux and brain penetration. sites.dundee.ac.uk/farnaby-group/…

Proteome integral solubility alteration via label‐free DIA approach (PISA‐DIA), game changer in drug target deconvolution …iencejournals.onlinelibrary.wiley.com/doi/abs/10.100… --- #proteomics #prot-paper

Thank you Biochemical Society! We are honoured to receive this award. It highlights the importance of team science and partnership working.