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What a great start to the week Karolinska Institutet recruited their 100th patient to the PRISM Trial!! 🍾🎉Keep up the good work Sandra Mansson Olof Brattström and team!

Assessment of functional capacity before major non-cardiac surgery: results of the METS study. thelancet.com/journals/lance…

METS paper published today in Lancet - clinician evaluation of functional capacity VERY UNRELIABLE - great contribution from UK investigators under leadership of @rupert_pearse #teamanaesthesia thelancet.com/journals/lance…

Denny Levett on benefit of post-op ICU. Observational data suggest no benefit post-op ICU admission compared to ward-based care. ISOS team EBPOM #EBPOM18

Mev Gooneratne on intra-op hypotension @triperioperati1 #ebpom18

Moderate and severe anaemia associated with increased risk of death after surgery. New data from ISOS team & buzzlogic. doi.org/10.1016/j.bja.… William Harvey Research Institute @rupert_pearse

The latest ISOS team paper on anaemia and outcomes after surgery. William Harvey Research Institute British Journal of Anaesthesia APORG (African Perioperative Research Group)

Relationship between preoperative anaemia and risk of complications after surgery. New data from ISOS team & buzzlogic. doi.org/10.1016/j.bja.… William Harvey Research Institute @rupert_pearse

New ISOS team paper published today in BJS Global Surgery edition. Grading the severity of postoperative complications in global health research: a comparative analysis.

🆕 #Videoabstract 📽️ #vodcast from our #GlobalSurgery 🌏 special issue: ➡️ Tom Abbott from William Harvey Research Institute discusses the ISOS paper on grading the severity of postoperative complications in global surgery research 🔗📜 onlinelibrary.wiley.com/doi/10.1002/bj… 📺 Full clip: youtube.com/watch?v=1VADUO…

Amazing effort by all investigators. Thank you for all the hard work. With just over 600 participants left to recruit, let’s aim to finish before August!

Thanks @rupert_pearse! Team effort, including: Mandeep Kaur buzzlogic Bruce Biccard Mike Gillies and ISOS team investigators. Great example of collaborative international research 🙂👍👌William Harvey Research Institute World Health Organization (WHO) British Journal of Anaesthesia

4700 participants recruited to PRISM Trial !!! Only 100 to go! This is a fantastic achievement and we are now very close to the end! Thank you to all involved. Can we finish by the end of October? @rupert_pearse

Our modelling analysis suggests that ~750,000 operations may have already been postponed in NHS England due to COVID-19, which could increase to ~2.2 million by March 2021 as elective surgery is gradually reintroduced medrxiv.org/cgi/content/sh… (Pre-print. Not yet peer-reviewed).

We estimate that the financial cost of clearing the current backlog of postponed operations in NHS England is ~£1.3bn. This could increase to over ~£5bn by March 2021 as the reintroduction of elective surgery will be gradual. medrxiv.org/content/10.110… (Pre-print. Not peer-reviewed)

1/Our analysis of all surgery in England since start of the pandemic found that patients with SARS-CoV-2 have much greater risk of death compared to patients without infection. medrxiv.org/content/10.110… @rupert_pearse Alex Fowler Tom Dobbs CCPMG

1/ Increasing numbers of patients aged 75 or older are undergoing surgery, but it is unclear whether these treatments are needed or whether they improve quality of life. academic.oup.com/bjs/article/10… Alex Fowler @rupert_pearse BJS

Published today in British Journal of Anaesthesia are two papers describing the impact of SARS-CoV-2 on surgical patients in England and Wales led by teams from William Harvey Research Institute & Swansea University Tom Dobbs @rupert_pearse Alex Fowler CCPMG bjanaesthesia.org/article/S0007-… & bjanaesthesia.org/article/S0007-…

Published today in The Lancet Respiratory Medicine is the final report of PRISM Trial, an international multi-centre phase-3 randomised trial of routine postoperative CPAP to prevent pneumonia, re-intubation & death after major abdominal surgery sciencedirect.com/science/articl… @rupert_pearse William Harvey Research Institute

May 2018 Infographic: The Eyes Have It: Factors that Influence Intraocular Pressure (IOP) goo.gl/Y2vs5V