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My latest review: Pluripotent stem cells for the systems biology of embryonic patterning doi.org/10.1016/j.ydbi…

I want to congratulate the four awardees of the UM Postdoctoral Pioneer Program. For more info please check out the website: umichpioneerprogram.org UMCDB U-M Rogel Cancer Center UMPhysiology Michigan Research @umichOGPS Idse Heemskerk Jason Spence Lyssiotis Lab #MP3 #postdoc_umich #umich

check out our preprint on PGCs in micropatterned stem cell colonies biorxiv.org/content/10.110…

Biology must generate ideas as well as data nature.com/articles/d4158… This x1000 - really excellent article. For example, there's currently too much single-cell-seq data in developmental biology without scientific ideas attached.

The full version of our Elife paper "Efficient differentiation of human primordial germ cells through geometric control reveals a key role for Nodal signaling" is now online: doi.org/10.7554/eLife.… eLife - the journal

Studying human development in a dish via @MHealthLab labblog.uofmhealth.org/lab-report/stu…

never forget the scale bar! Tim Stearns when biology meets astronomy: cell vs nebula, centrosome vs dying star! Etienne KLEIN

Our teams of faculty and trainees make important discoveries thanks to a strong interdisciplinary and innovative research environment. Come join us! Apply Now careers.umich.edu/job_detail/224…

Check out our new preprint: The time integral of BMP signaling determines fate in a stem cell model for early human development biorxiv.org/content/10.110…

The time integral of BMP signaling controls differentiation: biorxiv.org/content/10.110…

We hypothesize that there are multiple equivalent paths from pluripotency to primordial germ cell-like cells: sciencedirect.com/science/articl…

Can metabolic processes instruct cell fate decision making during embryonic development? In our new preprint, we show an important role of glycolytic activity for the development of endoderm and mesoderm through the regulation of Nodal and Wnt signalling. biorxiv.org/content/10.110…

Check out our comment in Nature Methods with Vikas Trivedi rdcu.be/dsVXu

Now published in Nature Communications : "Time-integrated BMP signaling determines fate in a stem cell model for early human development" by Seth Teague et al. rdcu.be/dySJF

Check out our latest preprint on FGF/ERK signaling in 2D gastruloids: biorxiv.org/content/10.110…

Our work on FGF/ERK signaling in 2D gastruloids is now published as a reviewed preprint in Elife (revisions to come) doi.org/10.7554/eLife.… eLife - the journal

Our work on mesoderm development in 2D gastruloids is now published in Nature Methods: nature.com/articles/s4159…

The Health Lab news highlights research by Bohan Chen in the Idse Heemskerk lab. The article, "Improved Model System Allows Researchers to Study Embryo Development," explores new findings about embryo formation. Read more michmed.org/NYY2z #UMICHResearch #GoBlueMed