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Dear nephrologist: Not all #renalpath diagnoses are created equal. Some are much less than others, and acute tubular injury/ ATN is among the least. Here are the reasons: 1. If we look hard enough, tubular injury is almost always present in the kidney bx. 1/

Critical data - while bone scintigraphy has resulted in a massive improvement in our diagnostic abilities in transthyretin amyloidosis, it remains insufficient with significant limitations. In this report, patients with L58H variant had closed to 90% false negative PYP scans. In

Ex vivo #CRISPR-Cas9 knock out PR3 autoantigen in HSPCs prevents PR3-ANCA-driven neutrophil activation while preserving immune function. While aHSCT would still be required, this opens the door to sustained, drug-free remission in PR3 #ANCA #vasculitis! doi.org/10.1016/j.kint…

Biopsy-based Transcriptomics Support Rejection Monitoring through Repeated Kidney Allograft Biopsies KIReports #openaccess buff.ly/7J8khEn

Congratulations to Andrew Rule and Denic - AI derived multi class model evaluating chronic changes in kidneys. Chronic changes from AI-based detections associates with ⬇️ GFR & kidney failure post radical nephrectomy for tumor.

J'ai ri.

Quel papier! Merci pour lui…et pour nous. Mort de Brian Wilson, fondateur des Beach Boys : sous la plage le génie – Libération liberation.fr/culture/musiqu…

Absolutely insane amount of data in this resource from Chris Mason The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs biorxiv.org/content/10.110… Spatial data on 15million cells from 100 donors across multiple ages, mainly GI

In this multi-center study we describe 3 distinct phenotypes of patients with PLA2R-MN using unsupervised machine learning! ⁦Jing ^_^⁩ fernando fervenza⁩ ⁦Shane Bobart, MD, FASN⁩ ⁦Wisit Cheungpasitporn MD FACP | FASN | FAST⁩ ⁦Maria Jose Soler⁩ ⁦NDT⁩ academic.oup.com/ndt/advance-ar…

Triste soubresaut d'un journal qui se meurt

ALECT2 amyloidosis in a patient with myeloma cast nephropathy - Kidney International kidney-international.org/article/S0085-…

A membranous pattern is occasionally present in Fibrillary GN Notice randomly arranged fibrils in the subepithelial regions. DNAJB9-positivity is seen in a similar distribution by IHC. Can be mistaken for membranous nephropathy: doi.org/10.1016/j.ekir…. #renalpath #PathTwitter

Thrilled to share our work and truly honored to share senior autorship with fabiola.terzi ! Thanks Science Translational Medicine for publishing our work ! science.org/doi/10.1126/sc…

THE INSTITUTE premieres this Sunday. Cool kids raging against the machine. MGM+. It's really good.

Isaac Asimov was so ahead of his time Absolutely nailed it here

kitware.com/webinars/integ…

In our new study in KI Reports we show how longitudinal monitoring of serum anti-podocin antibodies guided immunotherapy in a difficult case of steroid- and rituximab-resistant nephrotic syndrome sciencedirect.com/science/articl…

The comment period is open for the 2024 Banff meeting report! Renal Pathology Society #renalpath #transplant

Longitudinal Study of the Vascular Glycocalyx and Urinary Podocyte Markers During Pregnancy Oscar Garcia, MD Jing ^_^ Vesna Garovic ahajournals.org/doi/10.1161/JA…

We're excited to share a new publication featuring one of our staff physicians, Dr. Alejandro Best, alongside many other excellent renal researchers! #renalresearch #renalpath It's titled, "Renal Pathology Society/International Kidney and Monoclonal Gammopathy Research Group