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Delighted to share our mini review by Prof. Ikonen and me IkonenLab on intracellular cholesterol flow between membranes. The mesmerizing lipid cholesterol is so well known, but its behavior still remains largely unknown. Developmental Cell. authors.elsevier.com/c/1d4xe5Sx5gmI…

New release fresh from our lab revealing how ORP2 controls FAK activation and LDL-cholesterol plasma membrane delivery by promoting bidirectional cholesterol/PI(4,5)P2 exchange between late and recycling endosomes! Medicine and Health, University of Helsinki STEMM Research Program embopress.org/doi/full/10.15…

ORP2 couples LDL-#cholesterol exchange between late and recycling #endosomes to FAK activation and cell motility - new results by Kohta Takahashi et al IkonenLab University of Helsinki and collaborators embopress.org/doi/10.15252/e…

Elina Ikonen has received 2021 Avanti Polar Lipids/EBSA Award that recognizes the most important European scientific contributions in the understanding of biophysics of #lipids. Medicine and Health, University of Helsinki STEMM Research Program ebsa.org/portal/prize-a… 🥳💐

Know what it feels like to be an Avanti Award Winner? Dr. Elina Ikonen does! Find out what winning the award means to her, as well as insights into current lipid research trends in the Avanti Award Winner interview series! bit.ly/3APb4FJ

Very nice 2nd day of the ITN EndoConnect kick-off meeting, great lectures of judith klumperman and Kristiina @Ikonenlab, great opportunities for the PhDs to set up collaborations. Research UMCG, tomorrow training in communication, data management, seminar of our Dean Marian Joëls UMCG

STEMM Retreat is happening: The first day has been full of scientific interactions in presentations, workshop, and poster session - And most importantly we're finally meeting each other in person! Medicine and Health, University of Helsinki University of Helsinki

Excited to share our collaborative effort on the role of seipin at ER-mitochondrial contact sites, now out in Cell Reports! cell.com/cell-reports/f…

Are you curious about the function of DFCP1 in autophagy? Have a look at our latest preprint - we find that it is an ATPase involved in selective autophagy! Kay Schink Harald Stenmark Terje Johansen Veijo Salo Centre for Cancer Cell Reprogramming IkonenLab Tan Kia Wee biorxiv.org/content/10.110…

We are recruiting a Doctoral Researcher! Those of you who have a strong interest in cell biological approaches to study intracellular transport and metabolism of lipids are warmly encouraged to apply. ITN EndoConnect Medicine and Health, University of Helsinki www2.helsinki.fi/en/open-positi…

We are looking for a highly motivated PhD student for our consortium to work on a project on intracellular transport and metabolism of major membrane lipids at the University of Helsinki! To find more about the position, the resear…lnkd.in/dNMN-Db4 lnkd.in/dTfMmZbM

I'm very excited to share our new article on #mitophagy #lipids and #iron now out in The EMBO Journal!! 🎉🙌 Congratulations Maeve Long et al, especially to our outstanding collaborators @whitworth_lab Ganley Lab IkonenLab @UmeaUniversity 🧵 1/n #teamwork embopress.org/doi/full/10.15…

The call for HiLIFE_Helsinki Tenure Track Assistant and Associate Professors is open for one more month. Save the date and apply by 25.8., or share with your #lifescientist friends and colleagues if you think they would be the perfect fit for this. helsinki.fi/en/hilife-hels…

Out in Cancer Research our study showing that in operable #PancreaticCancer, regions distant from malignant cells already display proteomic changes related to lipid metabolism that affect prognosis and may be pharmacologically targeted. aacrjournals.org/cancerres/arti…

Out in Nature Communications our fine collaboration with Abdou Rachid Thiam and Ilpo Vattulainen on how cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols. nature.com/articles/s4146…

Scientist from Abdou Rachid Thiam and IkonenLab report formation of supercooled liquid crystalline lipid droplets by that cholesterol esters. #lipiddroplet, #cholesterol, #lipidtime nature.com/articles/s4146…

Happy to share our new work on human cell engineering with an improved version of auxin-inducible degron system. A great collaboration between IkonenLab IkonenLab and Taneli Lab Taneli Raivio in University of Helisinki. biorxiv.org/content/10.110…

New paper from our lab on how boosting homozygous knock-in efficiency enables robust generation of human auxin-inducible degron cells, by Shiqian Li et al. in Genome Biology 🥳

🎉Thrilled to share our most recent work on how the lipid environment finely regulates the Golgi V-ATPase. A big THANK YOU to everyone in the Ikonen lab IkonenLab @MiesvdStoel X Paul Ph.D 🇫🇮🇺🇦, and our collaborators. 🔬Read more: biorxiv.org/content/10.110…