Why are you confused? There's just genes. And alternate splicing. And regulatory elements. And regulatory elements in the alternate splicing. And regulatory elements are transcribed. And RNAs can do things. And proteins can fold differently in different cell types. And...

Yesterday was a really good day. Maybe even a career high. I should be popping the 🍾. But with every high has to come a low, right? That’s how this works. Have you been getting your mammograms like you’re supposed to? I haven’t. 🧵 #KidneyWk #WomenInMedicine

Our paper on the SMC-specific TRAP-Seq mouse model is finally out! This was one of the 1st projects in my lab 10 years ago before scRNA-Seq was on the scene. Great for obtaining cell type specific data more affordably. Here applied in #atherosclerosis academic.oup.com/cardiovascres/…

Prof. Minna Kaikkonen-​Määttä secures two million euros of European Research Council (ERC) funding – aims to redefine cardiovascular risk assessment. She was granted ERC funding for the second consecutive time, which is a rare achievement.Kaikkonen Lab A.I. Virtanen Institute uef.fi/en/article/min…

New research reveals how a specific #CoronaryArteryDisease variant rs880890 curtails CALCRL expression by disrupti... #EndothelialCells Ilakya Selvarajan Kaikkonen Lab @stevejwhite77 GroupLaakkonen Ilakya Selvarajan @UAromlab Aarthi Ravindran Kaikkonen Lab ahajournals.org/doi/abs/10.116…

Thank you #sydäntutkimussäätiö for the continued support to our research! Special congratulations to Mehvash Ilakya Selvarajan Prosanta Singha and Valtteri Nurminen #cardiovascular #research #grant

The coffee break is over and the seminar presentations continue! Next is Ilakya Selvarajan from the University of Eastern Finland with her topic "Identification of MAFB as an adipose tissue macrophage master regulator in adipose tissue”. #FibroHealth University of Oulu #6GESS DigiHealthOulu

Join me and my fellow researchers as we recount how the tiny zebrafish from India became biology’s most loved model organism. ⁦nature⁩ ⁦Nature India⁩ ⁦CSIR-IGIB⁩ ⁦CSIR, India⁩ ⁦National Centre for Biological Sciences⁩ ⁦CCMB⁩ nature.com/articles/d4415…

GWAS of unexplained recurrent pregnancy loss in 1,728 cases and 24,315 female controls of Japanese ancestry. In addition to MHC locus, the authors find a rare CNV deleting CDH11 (cadherin 11) increases the risk of pregnancy loss by >3-fold compared to non-carriers. Sonehara,

I’m thrilled to share that our work from the VA Research is finally out in Science Magazine ! We dive deep into the genetic architecture of 2,068 traits using data from the VA Million Veteran Program, comprising 635,969 Veteran. science.org/doi/10.1126/sc…

Amazing collaboration FinnGen Estonian Biobank deCODE genetics UK Biobank #DBDScohort #MoBAcohort identified genetics involved in postpartum bleeding- the condition accountable for most maternal deaths globally 🌍 nature.com/articles/s4158…

The PhD study of Ilakya Selvarajan, MSc, focused on cell type specific genetic regulatory mechanisms in human coronary artery disease. PhD defence on 12 Sep 2024 in Kuopio, live stream online. Kaikkonen Lab UEF Doctoral Programme in Molecular Medicine uef.fi/en/article/doc…

Another PhD defense coming up soon—keeping the streak alive! I am so looking forward to Ilakya Selvarajan's big day! 🎓🔥 #PhDStreak #OnARoll

Excited to welcome Helena Kilpinen ([email protected]) to Kuopio next week! PS. Coffee served before the seminar by #MetabolicsRC Also looking forward to the great scientific discussion as she serves as the opponent for Ilakya Selvarajan defense the following day (MS301) uef.fi/fi/tapahtuma/f…

Congratulations to our lab's newest PhD, Dr. Ilakya Selvarajan, for her great achievement! Your dedication is inspiring! A big thank you to the opponent Helena Kilpinen ([email protected]) for engaging discussion. Looking for the evening party 🥳 UEF Doctoral Programme in Molecular Medicine

Kaikkonen Lab Ilakya Selvarajan UEF Doctoral Programme in Molecular Medicine Thank you Minna for the invite and Ilakya Selvarajan for the great discussion today. It was a pleasure to take part in your special day!

We performed the largest GWAS of hot flashes to date. Remarkably, the top locus lies in the TACR3 gene, which codes for a receptor critical for the generation of hot flashes. Co-author Crandall first discovered this locus, which is now incredibly significant (p=3.4e-40). 3/10

I have written only one paragraph of this new grant, and I have already climbed the summit of joy (hey, at least I got started) and plumbed the depths of despair (what is this sh*t?!)

Doing good science is 90% finding a science buddy to constantly talk to about the project.

Ilakya Selvarajan tutki väitöstyössään sydän- ja verisuonitautien, kuten sepelvaltimotaudin, geneettisiä ja toiminnallisia mekanismeja. Nyt väittelijä pyrkii kartuttamaan tutkimukseen liittyviä johtamis- ja neuvontataitojaan. kemia-lehti.fi/vaitos-sepelva… #kemialehti