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High #WaistCircumference stands out in a #MendelianRandomization as the biggest driver of #HealthCosts among 15 risk factors studied. 1/2 HT: Andrea ganna conscienhealth.org/2023/09/cause-…

Lab dinner at #AHA23! AHA Science Mass General Heart Broad Institute Art Schuermans Jiwoo Lee Satoshi Koyama Sarah Urbut Michael Honigberg, MD, MPP Nishu Uppal So Mi Jemma Cho Aeron Small Akl Fahed Rachel Bernardo

Delighted to share our genomics/proteomics study among ~44K individuals to uncover novel biomarkers & pathways for common CVDs (CAD, HF, AS, AF). Led by Art Schuermans Ashley Pournamdari & with Michael Honigberg, MD, MPP. medrxiv.org/content/10.110… medRxiv [1/x]

Our study led by Harvard Medical School HST student Jiwoo Lee examines the overlapping and distinct lipoprotein features connected to common vascular disorders. Key insights include the role of small VLDL particles and TGs within HDL particles in ASCVD risk. ahajournals.org/doi/abs/10.116…

Metabolomic landscape of common vascular conditions shows complex role of lipoproteins in atherosclerosis and thrombosis. Jiwoo Lee Jacqueline Dron, PhD Satoshi Koyama Tetsushi Nakao, MD PhD megan Gina Peloso Whitney Hornsby Pradeep Natarajan ahajrnls.org/4fFjFjQ

Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery: a multi-ancestry study in 10 960 individuals from 9 biobanks medrxiv.org/cgi/content/sh… #medRxiv

Thrilled to share our latest preprint!📜 A major project I’ve led during my PhD, examining how genetic factors influence weight loss outcomes from GLP1 receptor agonists and bariatric surgery across 9 biobanks and 10,960 individuals. 📷#Genetics #obesity #MedicalResearch

Are genetic factors that influence body weight also affecting the effectiveness of GLP-1 RA drugs and bariatric surgery for weight loss? In this collaboration, we try to answer this question Check it out 👇

And also this year #ASHG2024 is starting. Looking forward to see everyone, reach out if you want to meet! See 👇 the work presented by the team, including a plenary reporting the work of the genCOST consortium.

What does the circulating proteome teach us about common heart diseases? Thrilled to share our analysis identifying new biomarkers, drug targets, and prediction models for these conditions. Co-led by Ashley Pournamdari, with Michael Honigberg, MD, MPP and Pradeep Natarajan nature.com/articles/s4416… (1/x)

🚨 New paper 🚨 Do known genetic factors for obesity affect weight loss from GLP1-RA (Ozempic) or bariatric surgery? 🔍 10,960 people, 9 biobanks, 6 countries 🧬 Minimal genetic impact on GLP1-RA response 📉 Modest effect after surgery nature.com/articles/s4159…

Lee et al. perform mathematical modelling on clinical ascertainment of Huntington’s disease. Higher population frequencies of expanded huntingtin CAG repeats and underascertainment rates indicate HD prevalence could be double the current estimates. Read at buff.ly/YPc8Fw5

Tiffany Bellomo Mass General Vascular is a rockstar! And a terrific mentor to Jiwoo Lee Harvard Medical School HST student!

It's #VenousPhotoFriday! Do you know what this photo is of?! If you guessed hypersensitive reaction you'd be correct! Check out todays featured article on HSR after cyanoacrylate closure and what YOU need to know about it! jvsvenous.org/article/S2213-… #VenousEd

Two members of the EVS Mentorship Program describe how mentorship impacted their journey to vascular surgery! Mentorship families will meet at the annual meeting in September. See you there!🥳 events.easternvascular.org/evs-mentorship…

So excited to share my experience with the Eastern Vascular Society Mentorship Program! It's been an honor to serve on the committee—and an even greater honor to work with Jiwoo Lee! Any program would be incredibly fortunate to have such a talented future vascular surgeon!

So delighted to work with all-stars Tiffany Bellomo Mass General Vascular & Jiwoo Lee Harvard Medical School and see the culture of support and mentorship propagate within the lab Mass General Brigham Research Broad Institute Harvard Medical School