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Interested in #immunometabolism #immunity #metabolism #monocytes? Check out this preview I wrote (with my supervisor Ana Domingos) on a fascinating, dogma-busting paper from the Swirski lab! lnkd.in/eNFXk_if Thank you Emma Haberman for the figure artwork!

Here it is! science.org/doi/10.1126/sc… A years-long project that took a lot of turns to get to this point through the tremendous work of Matthieu Rousseau, Livia L Mariano, and Tracy Canton ☺️☺️☺️🎉🎉🎉🍾🍾🍾

Today we're excited to hear from Judy Sayers, @KatBochtler, Yitao Zhu, Naroa Ibarra-Aizpurua, Kaitlyn Dennis, Emma Haberman, Florina Szabó, Anna Zerio & Conan O'Brien on day one of the 2023 Sherrington Talks by third year DPAG DPhil #students! From 1pm in the Blakemore Lecture Theatre

Congratulations to our four prize winners of the Sherrington Talks 2023! Our two winners are Conan O'Brien & Antara Majumdar 🧠👩🏽‍🔬💫 and our runners-up are Benjamin Bréant & Kaitlyn Dennis! Read more on the DPAG website: dpag.ox.ac.uk/news/sherringt…

John Lukens I think a summary of the last few decades of MØ literature is that macrophages are almost everywhere and that they serve more homeostatic functions than their bona fide immune-related activities. They are a para-immune cell.

Macrophages ALWAYS win. Reprogramming tumour-associated macrophages to outcompete cancer cells | Nature nature.com/articles/s4158…

Is there anything macrophages don’t do??!

Ever wondered how dendritic cells that have never been at the site of a challenge know how to drive the right kind of T cell response? We did, and it’s finally come together! science.org/doi/10.1126/sc… Science Immunology

Fascinating new framework for single cell seq analysis I had the pleasure of learning about from Davi himself. A particularly relevant method for understanding the functional heterogeneity of T cells - check it out!!

Great paper, yet another proof that the fixation you use for your staining can make a huge difference: just look at figures 2 and 7! science.org/doi/full/10.11…

Macrophages strike again! This time, infiltrating macrophages trigger cell death of pineal gland innervating neurons, causing functional denervation, impaired melatonin production, and sleep disruption! Not “just” immune cells! science.org/doi/10.1126/sc…

This is pretty awesome

Yet another reason why macrophages are awesome 🤩

Very tired at the last day of #BSI23 after a 5am poster presentation at the afterparty... Invite Conan O'Brien and Emma Haberman to your parties if you want some proper immunology entertainment 😅

What a fantastic #BSI23 and what a pleasure to be able to present my PhD work to such an engaged audience of immunologists! My Fitbit said I was in fat burning mode for the duration of my talk too which may help to offset some of the indulgences that followed! 👨‍🔬🔬🍺 🍔

Massive congratulations to Emma Haberman for getting this out before Christmas! Adipose tissue perineurial protect against obesity by promoting thermogenesis in brown adipose tissue! Super cool work and so so well earned!! 🤩👩‍🔬👏👏 See now in Immunity #neuroimmunology

Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders dlvr.it/T08X6R

Habemus Doctore Department of Physiology Anatomy & Genetics (DPAG) ! 🎉 Congrats, Conan O'Brien 🎓 Conan O'Brien on earning your PhD from Department of Physiology Anatomy & Genetics (DPAG)! It was a pleasure mentoring you on this incredible journey. Special thanks to Jeremy Taylor and Mikael Karlson for their examination of his exceptional thesis!

Microglia are the brain's resident immune cells. Their job is to patrol the brain's blood vessels looking for invading pathogens to gobble up. But what happens when they go rogue? Great article on brain-macrophages from the BBC bbc.com/future/article…