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In Science Immunology this week, Emma Louise Houlder, Koen Stam, Maria Yazdanbakhsh, Meta Roestenberg, & al. at LUMC Parasitology track how immune responses evolve over time in #schistosomiasis using controlled #Schistosoma mansoni infections of human volunteers! bit.ly/SciImm_adl1965

The September issue of Science Immunology is live! This week: #human #MAITCell heterogeneity across tissues; dev origin of #monocytes & #epidermal niche signaling imprint #LangerhansCell identity; & #IgE-producing #PlasmaCells have a unique phenotype! New content added each week!

What a fantastic ImmunOctoberfest conference! Thank you, Dietmar, Ben, & Anna for organizing such a masterful meeting! We are already looking forward to Memphis 2026!

The latest issue of Science Immunology is out now! New content every week! Check it out!

Last week's ICIS 🦋 @cytokinesociety.bsky.social #cytokines2024 meeting in Seoul was amazing! To celebrate, Science Immunology has just released a free sample collection of papers highlighting the immunology of #cytokines! Articles are free online to read for the next 6 weeks! bit.ly/SciImm_free

The November issue of Science Immunology is out now! This week: new insights into #DC #CrossPresentation; a #Focus on #monocyte heterogeneity; & #intravital #microscopy shows how #KupfferCells seed #liver #sinusoids in #EarlyLife! Additional content each week! Check it out!!!

Our cover story this month features some absolutely exquisite work from Bruna Araujo David, kubeslab, and colleagues! We are so excited to share it!

This week in Science Magazine: Jerika Barron, Ari Molofsky, Anna Molofsky, & colleagues report that #ILC2 promote #postnatal #synapse formation in the #brains of #mice. An absence of ILC2 leads to impaired #social #behavior in adult mice! bit.ly/Sci_adi1025

This week in Science Immunology: some fantastic work from Prof. Akiko Iwasaki & collegues! Be sure to check out her really helpful tweetorial below!

This week in Science Immunology: Demaria Olivier, Eric Vivier, & al. use tetraspecific #NKCell engager (comprising an α-#NKp46 Ab fragment + #IgG1 #Fc fragment + #IL2 variant + α-#CD20 Ab) to target #BCell-specific #NonHodgkin #lymphoma in mouse & NHP models! bit.ly/SI_adp3720

In Science Immunology last week, Zhang&al reported stability & expression of #ImmuneCheckpoint molecule #TIM3 regulated by palmitoyltransferase DHHC9. Peptidic inhibitor of DHHC9 accelerates TIM-3 degradation & enhances #CARTCell & #NKCell #antitumor immunity! bit.ly/SI_adp7302

Now in @sciimmunology, Ransmayr, Kaan Boztug, & al describe patients w #IEI caused by #biallelic #LOF mutations in #LTB. LTβR signaling shapes #human #SLO microarchitecture & immune function in ways unanticipated by earlier 🐭studies! bit.ly/40UiLeo

This week in Science Immunology, Jacki Heraud-Farlow, Carl Walkley & colleagues used a genome-wide #CRISPRscreen to determine that a GGNBP2– CNOT10/11 complex is required for the accumulation of unedited #immunogenic self-#dsRNA & its sensing by #MDA5! bit.ly/SI_adk0412

I am so looking forward to attending #Peritoneal Summit 15–17 JAN 2025 in beautiful Pontresina, coörganized by Prof. Joel Zindel, MD, PhD & @IngeKHermann! It should be a great meeting on burgeoning field of body cavity immunity! Come join us! Abstract deadline 30 NOV! peritoneal-summit.com

The December issue of #Science #Immunology is out now! This week: #MAITcell plasticity in #antibacterial immunity; how #inflammatory status of #lung before #COVID19 infection impacts #viral control; & #helminths utilize glutamate dehydrogenase to prevent #AAMs & #TH2 activation!

This is a public service announcement!

This is a public service announcement: late-breaking abstract submissions for #IUIS2025 will close tomorrow (May 6)! You can submit your abstracts here: iuis2025.org/abstracts/ I hope to see many of you this August in beautiful Vienna!!! #Immunology #CallForAbstracts #IUIS