Our paper introducing the concept of 'defensive tolerance' officially came out in Journal of Clinical Investigation. I would like to thank all our collaborators, as well as Drs. Molinari and Cravedi for their wonderful accompanying commentary. #defensivetolerance jci.org/articles/view/…

An evolutionary perspective to innate antiviral immunity in animals dlvr.it/TCRyJD

Innate immune responses against mRNA vaccine promote cellular immunity through IFN-β at the injection site nature.com/articles/s4146…

An autoinflammatory syndrome-associated STING mutation supports formation of germinal centers containing immunocompetent cells in the lungs of irradiated mice following BMT- insight.jci.org/articles/view/… Study from@ImmunoKevin and colleagues Kristy Chiang Kate Fitzgerald UMass Chan Program in Innate Immunity

Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults biorxiv.org/cgi/content/sh… #biorxiv_immuno

1/ We are excited to share a simple yet powerful whole blood assay to detect human type I interferon (IFN) deficiency...

nature.com/articles/s4159… I hope this is a helpful review! Appreciate the opportunity to co-write this review in Nature Immunology with my mentor Kate Fitzgerald. Thanks to all the reviewers' comments which significantly elevated our work and thanks to the unsung artists for their art!

#InterferonsFriendsOrFoes?! Matthias Mann Lab Thierry Nordmann French Ji &co using single cell proteomics identify nature an IFN signature in macrophages & keratinocytes KCs in a fatal #skin disease showing that JAK inhibition prevents KC death, curing patients nature.com/articles/s4158…