🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Deadline Extension for Abstract Submissions Good news! The deadline for abstract submissions has been extended to Monday 28 October. This is your chance to showcase your research by submitting either an oral or poster presentation for CRISPR 2025. #crispr #crispr2025 #phage

Come work with us in the Laboratory of Protein Structure (@MarcinNowotny lab), aka LSB!

🚨 New preprint alert! 🚨 We're excited to share our latest work: "Towards a complete phage tail fiber structure atlas" 🦠🔬 of first author Victor Klein-Sousa We developed #RBPseg for segmenting and merging phage tail fibers using structural prediction tools. tinyurl.com/58cn2ew7

some heads up, The EMBO Workshop "CRISPR-Cas: from biology to therapeutic applications", to be held from 2–5 November 2025 in Sorrento Italy. Please retweet #CRISPR Stay tuned for the programe and registration here 👇 coming-soon.embo.org/w25-86

Vertebrate retrotransposons are the future of gene therapy. But how do they insert their genes? 🔥🔥 Thrilled to present part 2 of my postdoctoral work with The Nogales Lab Collins Lab UC Berkeley MCB where we investigate this using #CryoEM and transgene insertion in 🧪 and cells!

We cracked the tRNA specificity of FaRel2 toxSAS. A fun collaboration with the Suzuki Lab., Garcia-Pino Gemma C Atkinson and Polikanov. Out in Science Advances! science.org/doi/10.1126/sc…

Congrats Andriana and Cas for such a nice work! Nice to see one system dedicated to Lithuanian 🇱🇹 god for fermentation, bread and beer production - Rugutis or Rūgutis! 💚🤟

Happy to share our spotlight (with Guillermo Montoya at CPRatUCPH) in CellChemicalBiology, highlighting the groundbreaking work by Ilya Osterman & Sorek Lab on how #phages reconstitute NAD to bypass bacterial immunity🦠🛡️. Check it out here! rb.gy/n8w9na 🤓

Would you prefer to lead a lab alone or together with a science buddy? How interesting would be a research institute where joint labs are the standard?!

Our laboratory is looking for a postdoc with expertise in protein biochemistry and structural biology to work on novel pathways regulated by ADP-ribosylation of nucleic acids. Please RT.

Thrilled to share that our Zorya paper is now published online in Nature! It was an incredible team effort Philipp Popp Marc Erhardt SimonJackson —thank you to everyone who contributed to this work.Inga Songailiene Victor Klein-Sousa Aritz Roa Freddie Martin Yong Wang Alexander Harms ₳źiż

Excited to share our latest collab with Wenyuan Han's Lab! 🚨 Bacteria use dITP as an immune signal to activate NAD+-depleting effectors. Phages counter immunity by destroying dAMP (dITP precursor)! 💥🧬 Preprint 🔗: biorxiv.org/content/10.110…

I can add "Life's Engines: How Microbes Made Earth Habitable" by Paul G. Falkowski. What more can you recommend for next year?

Looking forward to this. gmc.vu.lt/en/events-and-…

RNA-guided systems span kingdoms, from bacterial immunity to eukaryotic gene regulation. How did they evolve? We traced the origins of CRISPR-Cas13 and identified its likely ancestor: an RNA-based toxin-antitoxin (TA) system. Here’s what we uncovered: cell.com/cell/fulltext/… 1/8

I highly recommend attending this amazing microbiology conference! 🦠🔬👩🏼‍🔬🧬🧪 Only a few more days to submit your abstracts! (April 1st ). Looking forwards! 🍻

Excited to see our work published in Science Advances! We present RBPseg, a method for structural prediction of #phage receptor-binding proteins. We applied it to diverse tail fibers and validated the predicted structures using #cryoEM. Read here: science.org/doi/10.1126/sc…

Impressive spacer selection mechanism by Cas9-adaptation supercomplexes - all pathway captured by #cryoEM #Cas9 🧬🧩🧵

Impressive work!