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NOW ONLINE! This review explores how enhancer hijacking drives aggressive #Leukemia through MECOM overexpression, highlighting potential new targets for #CancerTreatments. Also presented as a talk at the IJC Symposium on 14-Jan by Ruud Delwel 🔓➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl

NOW ONLINE! New research shows that radiation harms CD8+ T cells more in patients with #HeadAndNeckCancer than in healthy people —pointing to the ATM-Chk2 pathway as a potential way to protect these immune cells. 🔒 FULL ACCESS ➡️ doi.org/10.1002/ijc.35…

NOW ONLINE! This review explains how targeting the KMT2A gene, a key driver in aggressive #Leukemias, with Menin inhibitors like Revumenib is showing promise. Also presented as a talk at the IJC Symposium on 14-Jan by Florian Perner 🔓➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl

New study introduces a non-invasive MRI-based method using 3D printing and animal models to map and evaluate immune cells in #LiverCancer, offering a new way to predict immunotherapy response while accounting for tumor heterogeneity 🔓OPEN ACCESS ➡️ doi.org/10.1002/ijc.35…

NOW ONLINE! This review focuses on the prevalence of cohesion mutations, and their influence on chromatin organization and gene regulation across different #Cancer types. Also presented as a talk at the IJC Symposium on 14Jan by Zuzana Tothova 🔒➡️doi.org/10.1002/ijc.35… Union for International #CancerControl

NOW ONLINE! New research shows that the left and right tumors in bilateral Wilms tumor—an aggressive form of childhood #KidneyCancer — can be genetically distinct and respond differently to chemotherapy. 🔒FULL ACCESS ➡️ doi.org/10.1002/ijc.35…

#WorldImmunizationWeek Personalized dendritic cell vaccines show promise as a powerful, well-tolerated immunotherapy for high-risk pediatric solid tumours, especially when combined with immune checkpoint inhibitors. 🔓OPEN ACCESS ➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl

NOW ONLINE! New review by Florian Perner et al. focuses on how targeted epigenetic drugs, like the emerging SWI/SNF‑focused compounds, are reshaping #CancerTherapy. Also presented at the IJC Symposium on 14-Jan by Prof. Michael Lübbert 🔓➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl

NOW ONLINE! Blocking both the synthesis and uptake of polyamines kills leukemia cells and delays disease progression, thus, offering a new treatment approach against #AcuteLeukemia 🔒 FULL ACCESS ➡️ doi.org/10.1002/ijc.35…

Today is #WorldOvarianCancerDay! The team of Prof. NicolineHoogerbrugge show that the Tumor-First workflow boosted genetic testing for ovarian cancer from 50% to 85%, improving detection of risk variants. #NoWomanLeftBehind 🔓 ➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl World Ovarian Cancer Day & WOCCoalition

NOW ONLINE! New research identifies NFL and GFAP as promising biomarkers for neurological immune-related adverse events from immune checkpoint therapy. #Immunotherapy 🔓OPEN ACCESS ➡️doi.org/10.1002/ijc.35…

New review by Isabelle Seufert et al. shows how changes in genome structure & protein assembly drives cancer by disrupting enhancer-promoter communication and targeting it in #CancerTherapy. Also presented at the IJC Symposium by Karsten Rippe 🔓➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl

Today is #ClinicalTrialsDay! JMT103, a RANKL-targeting antibody, safely and effectively reduces bone turnover in cancer patients with bone metastases, offering a promising option to ease complications. #PoweredbyPurpose #CTD2025 🔓 ➡️ doi.org/10.1002/ijc.35… Union for International #CancerControl ACRP - Assoc. of Clinical Research Profession

NOW ONLINE! New research shows that SAMHD1, a dNTP hydrolase, is linked to better outcomes and could serve as a promising #Biomarker in early breast cancer, especially in basal-like and HER2-enriched subtypes. 🔓 OPEN ACCESS ➡️doi.org/10.1002/ijc.35…

NOW ONLINE! New Study from IARC estimates global burden of cutaneous #melanoma (CM) caused by excess #UV onlinelibrary.wiley.com/doi/10.1002/ij…

NOW ONLINE! New research shows that tumor deposits in #ColorectalCancer signal a more aggressive disease and worse prognosis, suggesting their inclusion for accurate CRC staging. 🔒 FULL ACCESS ➡️ doi.org/10.1002/ijc.35…

On #WorldNoTobaccoDay, let's raise awareness: Snuff use is linked to higher risks of cervical, eye, and adnexal cancers, highlighting urgent health concerns . #UnmaskingTheAppeal FREE to read for 8 weeks! doi.org/10.1002/ijc.35… Melitah Motlhale Union for International #CancerControl #WNTD25

On #NCSD2025, let's highlight that repetitive transcranial magnetic stimulation shows promise as a safe, effective treatment for insomnia in cancer survivors, offering an alternative to cognitive behavioral therapy. FREE to read for 8 weeks doi.org/10.1002/ijc.35… Union for International #CancerControl