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"I think success is having a career where you enjoy it so much that you almost feel guilty that people pay you to do it because you are having so much fun every day." Wise words by our 2019 medicine laureate William Kaelin. #NobelPrize

Today, the U.S. FDA approved CRISPR-based gene therapy to correct the gene abnormality that causes sickle cell disease. Dana-Farber’s Stuart Orkin, MD, was the first to conceive of this genetic correction and the possibility of gene therapy for the disease. blog.dana-farber.org/insight/2018/0…

Check out the group's latest "Up-Assay"! sciencedirect.com/science/articl…

Truly honored and excited to be named one of the 2024 JCC fellows. Many thanks to KaelinLab and Sheng Tsinghua University for their incredible mentorships and support to make this possible. Thanks @JCChildsFund for the amazing opportunity, can’t wait to meet with other JCC fellows!

Congratulations to Dana-Farber’s Yanyan Hu, PhD, who has been named a 2024 Fellow by the Jane Coffin Childs Fund for Medical Research. This rare honor is bestowed on just a handful of promising researchers each year and is based on their doctoral research accomplishments,

We report a new role for HIF in the regulation of endogenous retroviruses! It was a big collaborative effort to explore the HIF-mediated transcription, expression, and HLA presentation of ERVs in kidney cancer and leveraging them for immunotherapy cell.com/cell/fulltext/…

Excited to share that work from my PhD lab is now available on Immunity ! Our findings identify the MEF2C-p21-CDK2-RB-NFκB axis as a critical pathway to maintain microglial homeostasis and highlight CDK2 as a potential therapeutic target for neuroinflammation.

Congrats Nitin! 🎉