Josh Hawley (@itsjoshsurely) 's Twitter Profile
Josh Hawley

@itsjoshsurely

Biophysics PhD student in the Papalopulu lab at the University of Manchester.

ID: 73215042

linkhttp://joshhawley.co.uk calendar_today10-09-2009 20:41:33

16 Tweet

55 Followers

65 Following

Steven Strogatz (@stevenstrogatz) 's Twitter Profile Photo

"If mathematical modeling is such a nifty tool, why has it taken so long for molecular biologists to incorporate it into their armamentarium?" Excellent, thought-provoking, under-appreciated article from 2015 by Tyson and NovĆ”k bmcbiol.biomedcentral.com/articles/10.11…

Papalopulu Lab (@papalopululab) 's Twitter Profile Photo

Cells in tissue are using ā€˜group chats’ to make decisions! Multiscale synthesis of fine-grained protein expression of HES5 reveals locally co-ordinated clusters and stripes that control rate of progenitor differentiation. bioRxiv: biorxiv.org/content/10.110… 1/5

Cells in tissue are using ā€˜group chats’ to make decisions! 

Multiscale synthesis of fine-grained protein expression of HES5 reveals locally co-ordinated clusters and stripes that control rate of progenitor differentiation.

bioRxiv: biorxiv.org/content/10.110…

1/5
Papalopulu Lab (@papalopululab) 's Twitter Profile Photo

Are you interested in lateral inhibition patterns emerging in #motilecells with #dynamic #protrusions ? Check out this #interactive multicellular neural tissue simulation tool made by Josh Hawley joshhawley.co.uk/neuraltube

Are you interested in lateral inhibition patterns emerging in #motilecells with #dynamic #protrusions ? Check out this #interactive multicellular neural tissue simulation tool made by <a href="/ItsJoshSurely/">Josh Hawley</a>  joshhawley.co.uk/neuraltube
Josh Hawley (@itsjoshsurely) 's Twitter Profile Photo

What happens when you give Notch a kick? Notch is a powerful signalling pathway for generating spatial patterns but often leads to stationarity. Here we describe how to make it dynamic and match tissue data by introducing perturbations to the signalling. doi.org/10.1098/rsif.2…

Papalopulu Lab (@papalopululab) 's Twitter Profile Photo

How do cells decode #TF oscillations and how does this impact development? We find #NGN3 protein oscillates in #pancreatic endocrine cells, #oscillations are likely decoded via fold-change and impact on the timing of differentiation, but not fate choice: papers.ssrn.com/sol3/papers.cf…

Papalopulu Lab (@papalopululab) 's Twitter Profile Photo

Our innovative study brings out the distinction between single cell and population-level #dynamic regulation. Single cell #oscillators can behave abnormally, despite this the population is normal due to cell #coupling mediated compensation. Development journals.biologists.com/dev/article/15…