Researchers Columbia University have invented a multimodal RNA sequencing method that achieves high-quality results from small volumes of frozen cancer tissues. engineering.columbia.edu/news/multimoda… Columbia Medicine Columbia Science Columbia BME Elham Azizi bizarMD Joy Fan Johannes Melms

Thank you very much JRNLclub for the opportunity to present our work on treatment-naive melanoma brain metastases. Work done at the bizarMD lab at Columbia University together with my colleague Jana Biermann, Ph.D. and amazing collaborators.

Thanks to National Cancer Institute for highlighting our work

New Treg story out today in Cancer Cell! A true team effort with (Twitterless) co-authors Aleks and Mikko from Califano Lab and Charles Drake labs at Herbert Irving Comprehensive Cancer Center. cell.com/cancer-cell/fu…

Very happy to see our study from the bizarMD lab at Herbert Irving Comprehensive Cancer Center published in Cancer Cell today! Thanks and congrats to Tricia Ho, Meri Rogava and the whole team. Link to pdf: sciencedirect.com/science/articl…

Online Now: The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity dlvr.it/SqyWXh

Thanks to National Cancer Institute for funding our work and for promoting our lab!

Happy to share our latest paper! Was such a pleasure to help finalizing this work, which Chong and I started long time ago in Ton Schumacher Lab . Congrats to everyone involved! cell.com/cancer-cell/fu…

Nothing better than two groups independently making pretty much precisely the same observation! Congrats riccardo.mezzadra Ton Schumacher Lab!!

A general thread on what Perturb-seq is, what it's good for, and how we managed to reduce its cost by an order of magnitude in our recent work: 1/33

Excited to share our new preprint! We developed methods for - and executed - pooled base editor screens of >100 critical T cell signaling genes in primary human T cells. We leveraged our findings to characterize critical protein domains and engineer superior anti-tumor T cells!

Very happy to share Meri Rogava's work on liver-metastatic organotropism in melanoma! Awesome work from discovery to mechanism. Great to have you as a post-doc colleague in the bizarMD group - first in Boston, then New York. Congratulations!!!

New research from bizarMD, shows that higher blood glucose levels 'attract' cancer cells to spread to the liver. Lowering blood sugar reduced metastases to the liver and enhanced the effectiveness of the immunotherapy drug they studied. Read more: cancer.columbia.edu/news/liver-met…

Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens go.nature.com/3yxjW7q

Happy to see this paper out! Congrats to the lab, especially MD/PhD student par excellence Zach Walsh

Excited to share a commentary on emerging challenges in understanding and targeting cancer genome instability to improve patient outcomes: bit.ly/3XoSstk Thanks to Cancer Discovery for the opportunity and to everyone else from the AACR NextGen Stars Program who contributed!

Excited to share a new paper: tinyurl.com/49u5e6by Cell: a framework to accelerate variant classification, diagnosis & treatment of immune disorders & genetic disorders more broadly. Led by superstar, juggernaut & future dermatologist Zach Walsh

Thrilled to share the latest work from my PhD in the bizarMD group! This has been a dream MD/PhD project, culminating in data that has already enabled access to precision therapy for a patient. Tweetorial below: