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In this paper, 3rd year graduate student 李春雨 (Chunyu Li) synthesized 25 natural products (!!) using a method of in silico library selection. Chunyu is a new type of student in our lab, having seamlessly blended calculation and synthesis. Take a look: tinyurl.com/mryjxh2w

***We are hiring!*** My group is looking for a postdoc with comp chem experience to join us at UT Dallas Chemistry from August '24. You can find out more about the position and submit your application here: jobs.utdallas.edu/postings/26587 Please share! #compchem

Prof. Ryan Shenvi, PhD, has won the 2024 A.R. Katritzky Junior Award by International Society of Heterocyclic Chemistry. His work in chemical synthesis and catalysis has greatly impacted medicine, agriculture, and materials science. Shenvi Lab continues to explore complex metabolites. More: ow.ly/384I50SrZHh

Check out live presentations in Denver from @olliesymes on our latest oxetanes work (4092373) and sulfonimidoyl fluoride SuFex reactions (4092377), as well as Adi Sahay on spirocyclic azetidine oxindoles (4090327, pubs.acs.org/doi/10.1021/ac…) #ACS

Sarah Patrick has a new @chemrxiv preprint out describing a continuous flow process for upgrading HFCs and HFOs. Great collaboration with Phil Miller and Bull Group Chemistry here is the link: chemrxiv.org/engage/chemrxi…

Congrats to Dylan and Stephen for their method to glycosylate cotylenol and access 14-3-3 protein-client molecular glues! tinyurl.com/2y45ck4n Donor linker design was aided by Stephen’s “autoDFT” and solved a common problem in terpenoid synthesis: contrasteric glycosylation.

Simple, Enantiocontrolled Azetidine Library Synthesis via Strain Release Functionalization of 1-Azabicyclobutanes. A fantastic collaboration with the Cravatt lab. A simple, modular, programmable approach to access complex stereopure azetidines through strain-release

Thanks J Org Chem/Org Lett! Maryne Dubois, Juan J. Rojas, Alistair Sterling, Fernanda Duarte, Milo Smith, Dr. James Mousseau, Andrew, Hannah, Phil and Charlie. pubs.acs.org/doi/10.1021/ac…

chemtwitter what is everyone doing for lithium metal suppliers?! We have birches to run and estimated deliveries of 2031 for lithium wire🤩 do people use the large rods? or granules kept in a glovebox?

wanna know too

Interested in 4-membered rings for drug discovery? See the latest from Bull Group Chemistry group on divergent synthesis of 3,3-disubstituted thietane 1,1-dioxides by catalytic carbocation formation in #JOrgChem 🔗 #OpenAccess go.acs.org/bdQ

If you like total synthesis and Wordle, check out Synthordle, a retrosynthetic analysis game created by Shenvi Lab associates Kevin Zong (GS 2) and Jonah Luo (HS sophomore!). rshenvi.github.io/synthordle/ Coming to Scripps Research Chemical Synthesis class in Winter ’25.

Delighted to report our studies on the synthesis and functionalization of BCB-sulfoximines Angewandte Chemie doi.org/10.1002/anie.2… (short 🧵)

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Our latest on oxetanes and azetidines. Congratulations and thanks to the team!

Check out our recent efforts in ChemRxiv to expand the chemical tractability of the proteome through NP-inspired photoaffinity probes. chemrxiv.org/engage/chemrxi…

"Unconventional reactivity of sulfonyl fluorides" sciencedirect.com/science/articl…

We are recruiting for a postdoctoral Research Associate in Synthetic Chemistry to work in C-H functionalisation. Come join us Imperial Chemistry! 3-year position. Closing 19-March-2025. shorturl.at/uwERp #Chempostdoc, #CHfunctionalization, #Heterocycles

** New PhD position ** We are advertising a chemical biology studentship with Profs Vilar and Mann, in collaboration with GSK, with ICB CDT ICB Centre of Doctoral Training . #automation, #Synthesis, #D2B. Fully funded at UK fees level. findaphd.com/phds/project/d…

Interested in strained rings or fluorine for medicinal chemistry - check out Hikaru’s work on divergent synthesis of difluorocyclobutanes, on ChemRxiv: doi.org/10.26434/chemr…