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🩺April #PaperofTheMonth: Distal & Medium Vessel Occlusions - Redefining the Boundaries of Mechanical Thrombectomy for Ischemic Stroke by Octavio Pontes Neto world-stroke-academy.org/news/the-paper… 🔗NEJM paper: nejm.org/doi/abs/10.105… Coming soon:🎥interview to Marc #StrokeEducation #EVT

Calling all #stroke and #NCD advocates attending #WHA78

#MondayTip The #NeurovascularUnit 🧠🌐 Originally seen as uniform, the NVU is now known as a heterogeneous, coordinated system interacting with systemic factors ⚠️➡️🛠️♻️ In stroke, immune cells initially worsen injury but later promote repair and recovery doi.org/10.1161/STROKE…

#MondayTip 🔎 In #ESUS, multiple embolic sources often coexist & are underestimated. ⚠️ Don’t chase one cause—European Society of Cardiology stroke council recommends assessing overall thromboembolic risk doi.org/10.1093/eurhea…

✍️New Protocol! 🌍🧠International Care Bundle Evaluation in Cerebral Hemorrhage Research (I-CATCHER) 👉Study to assess whether implementation of a care bundle improves functional outcome for patients with ICH in high-income countries Read more below👇 journals.sagepub.com/doi/abs/10.117…

Mechanical Thrombectomy for Large Ischemic Stroke: A Critical Appraisal of Evidence From 6 Randomized Controlled Trials ahajournals.org/doi/10.1161/ST… Stroke AHA/ASA

🚨Follow World Stroke Academy for #ESOC2025 news! 🕵️with INTERNEURONA we will be sharing everything about latest trials and more hot topics! 📍Helsinki 🇫🇮 🗓️ 21-23th May World Stroke Org Alianza Joven Latinoamericana contra el ACV

#ESOC2025 ✅ OPTIMISTmain: low vs higher intensity controls after IVT in NIHSS <10 👉🏻 non inferior in safety and efficacy 👉🏻cost savings 💲

#ESOC2025 ✅ASSET-IT: early tirofiban after IVT 👉🏻>mRS 0-1 and 0-2 at 90 day in Tirofiban arm 👉🏻 = sICH and mortality al 90 days

✅BRIDGE TNK💉 👉🏻TNK + EVT vs EVT in LVO AIS < 4.5 hs 👉🏻> mRS 0-2 in TNK 👉🏻> successful reperfusion in TNK 👉🏻 = first pass effect 👉🏻 = mortality and sICH

DISTAL sub analysis: 🧠 👉🏻volumen of saved brain in distal and MeVO with EVT vs BMT 👉🏻 good rescue >80% initial affected brain 👉🏻 > “saved” brain in EVT 👉🏻 > 80% saved brain > good outcome 👉🏻 >80% saved brain > TICI 2b-C

#ESOC2025 🏃🏻‍♀️ESCAPE MEVO sub analysis 👉🏻 prognosis by image 🧠 👉🏻EVT <12 hs not > good functional outcome 👉🏻 Good collateral status > benefit 👉🏻 ⏱️<180 min > benefit

#ESOC2025 💊ExCOA - CVT (trial and observation study) 👉🏻⏰short (3-6 m) vs long (12 m) anticoagulation 👉🏻 no diff in VTE (CVT, DVT, PE, abdominal thrombosis) 👉🏻 no diff bleeding 🩸 👉🏻 no diff mortality ☠️ (but > in long term ACO)

#ESOC2025 Sesión RCT Quick Take Va 🧵 1.- #OPTIMISTMAIN: protocolo baja intensidad monitoreo post rtpa (NIhSs<10) no inferior a standard thelancet.com/journals/lance…

Day 1 #ESOC2025 Canadian Stroke Consortium European Stroke Org Happening day, bridging with TNK and EVT is better, low intensity monitoring after IVT is safe, tirofiban post IVT may be helpful, and prolonged anticoagulation is not helpful in CVST.

#ESOC2025 🦵🏽EECP for improve cerebral vasodilatory reserve (on SPECT) in ICAD patient 1hr/d, 5 times/week 122 randomized patients, 58y, 61%males ✅EECP was associated with significant improvement in hemodynamic parameters

#ESOC2025 ☎️#PINGS2 trial for ambulatory BP management using basic phones, nurse-led strategy in Ghana 🇬🇭 ✅1ry out BP<140/90 at 12m: 👉67 vs 43% p0,001

#ESOC2025 #DEMDAS explored risk factors for developing post stroke #dementia Key factors: 🧠Previous brain health 🧠Stroke related factors 🫀Vascular and cardio metabolic, particularly pre & diabetes, reduced HDL-C

Day 2 #ESOC2025 Canadian Stroke Consortium 6 fascinating studies. An AI-support tool leads 32% RR in ischemic stroke, Ext Counter Pulsation increases CVR in ICAD, Community BP control with a Nurse-led approach, modifiable risk factors for dementia and fall prevention with tailored intervention