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I'm thrilled to share that our work on dicentric chromosome breakage has been published! If you're interested in DNA damage, chromosome fragility, centromeres, and spindle forces you might find this interesting. I sure do! 😄 academic.oup.com/genetics/advan…

If Darwin's finches were transposons, and the Galapagos islands were the Drosophila ovary, this cool new paper is all about the diversification of their beaks!🦜Congratulations Kirsten, @juliusbrennecke and all co-authors for this tour-de-force! 🥳👏 biorxiv.org/content/10.110…

Happy to see this paper out! With Amanda Larracuente, we review the implications of intragenomic conflicts mediating the co-amplification of gene families on sex chromosomes, and how this process might be fueled by sex-biased mutation. royalsocietypublishing.org/doi/10.1098/rs…

Congratulations to Julius Brennecke for securing one of this year’s European Research Council (ERC) Advanced Grants! Julius will study the arms race between transposons and host genomes. #ERCAdG More here: oeaw.ac.at/imba/research-…

Extremely cool talk by Maya Voichek (@juliusbrennecke lab): Drosophila retrotransposons encode membrane-associated micropeptide to traffic between somatic and germ cells! #ICTE2024

Genome defense requires innovation in specificity factors that recognize emerging selfish genes but does it require other types of innovations? We think so! Happy to share our preprint “Escalation of genome defense capacity enables control of an expanding meiotic driver” 🧵:

Timescales in Cell Biology

New paper led by Yadira Peña-García! Even though opossums have kids at 0.5 years, they still have typical male-biased mutation (though not quite as high as humans).

HHMI Investigator Nels Elde (Nels Elde) of University of Utah works at the crossroads of evolutionary genetics and cell biology to study one of the biggest battlefronts in science: host-pathogen interactions. Learn more about the Elde lab’s research: hhmi.news/49MaU4W

In a new Trends in Genetics piece, Amanda Larracuente and I spotlight an amazing work lead by Peiwei Chen uncovering Trailblazer—a regulatory innovation in the in piRNA pathway to suppress the meiotic driver Stellate. Check it out: authors.elsevier.com/c/1ktQOcQbJF8ya